Evidence map›Paper›PMID 42163117›Full record

ArticleBMC medical imaging2026

MRI features of fetal type I congenital choledochal cyst and parameter measurement of hepatobiliary development.

Leilei Gu, Duo Gao, Yimin Cao, Sicong Wang, Xuefang Han, Xuran Feng, Zhijuan Li, Huanyun Jing, Haiqing Yang, Zuojun Geng and 1 more

Abstract read
In one paragraph

Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Leilei GuDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Duo GaoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Yimin CaoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Sicong WangGE Healthcare, Beijing, 100010, China.
Xuefang HanDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Xuran FengDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Zhijuan LiDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Huanyun JingDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Haiqing YangDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Zuojun Geng *Department of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China.
Lixia Zhou *Department of Medical Imaging, The Second Hospital of Hebei Medical University, No. 215 Heping West Street, Shijiazhuang, Hebei Province, 050000, China. doctorzhou@hebmu.edu.cn.

Funding

the foundation of Medical Science Research Project of Hebei 20250531
6 · The paper itself

Abstract

objectivesTo observe fetal MRI findings of type I congenital choledochal cyst (CCC) and the developmental differences in abdominal organs between fetuses with CCC and normal controls.

methodsThis retrospective study included 90 normal fetuses and 31 fetuses with surgically confirmed CCC. MRI was used to observe CCC morphology, orientation, connection with bile duct or gallbladder, and its relationship with the liver edge. Cyst volume was calculated. Measurements, including the lung-to-liver signal intensity ratio (LLIR), liver (transverse and craniocaudal diameters, maximum cross-sectional area), spleen (long diameter, thickness, maximum cross-sectional area), gallbladder (long diameter, short diameter, maximum cross-sectional area), and portal vein diameter were compared between the two groups. Correlation between cyst volume and MRI parameters was analyzed.

resultsAmong the 31 CCC cases, 70.9% were female. The choledochal cyst morphology was elliptical in 26 cases. A "pointed apex sign" was observed in all cases. The inferior margin of the cyst did not extend beyond the inferior edge of the liver in 29 cases. The predominant orientation of the cyst was right upper to left lower in 26 cases. Compared to controls, CCC fetuses showed significantly larger splenic cross-sectional area, increased portal vein diameter, and higher gallbladder long-to-short diameter ratio (all P < 0.05).

conclusionCCC predominantly occurs in females. Fetal MRI findings typically show an elliptical lesion, generally not extending beyond the inferior edge of the liver, with a right upper to left lower orientation and a "pointed apex sign" at its superior margin. Affected fetuses exhibit an enlarged spleen, a widened portal vein, and an increased ratio of the gallbladder's long-to-short diameter. However, the cyst volume shows no correlation with these changes.

Indexed as

Choledochal CystLiverMagnetic Resonance ImagingPrenatal DiagnosisFemaleGallbladderHumansMalePregnancyRetrospective StudiesSpleenLiverMagnetic resonance imagingPrenatal diagnosisSpleenType I congenital choledochal cyst

Identifiers

PMID42163117
PMCPMC13366937

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.