Evidence map›Paper›PMID 42163085›Full record

ArticleBMC plant biology2026

Integrating morphological and phytochemical studies on some selected taxa of Lamiaceae Lindl. and Verbenaceae Juss.

Jackline S Garas, Mohamed A Salim, Mariam I Hussein, Magdy M Mourad, Nagwa M Ammar, Mohamed M Ayoub

Abstract read
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Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jackline S GarasDepartment of Botany, Faculty of Science, Ain Shams University, Cairo, Egypt.ORCID http://orcid.org/0009-0009-4201-958X
Mohamed A SalimDepartment of Botany, Faculty of Science, Ain Shams University, Cairo, Egypt.ORCID http://orcid.org/0000-0003-0967-4565
Mariam I HusseinDepartment of Botany, Faculty of Science, Ain Shams University, Cairo, Egypt.ORCID http://orcid.org/0000-0002-1206-3231
Magdy M MouradDepartment of Botany, Faculty of Science, Ain Shams University, Cairo, Egypt.
Nagwa M AmmarDepartment of Pharmacognosy, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Giza, Egypt.
Mohamed M AyoubDepartment of Pharmacognosy, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Giza, Egypt. mo.ayoub@nrc.sci.eg.ORCID http://orcid.org/0000-0001-7081-4745

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLamiaceae and Verbenaceae are taxonomically sister families, belong to the order Lamiales. They are well known for their phytochemical constituents with bio-active properties, but considerable taxonomic difficulties in discriminating between the two families have been reported. The present study aims to explore the morpho-anatomical characters (stem and lamina) of 11 selected species bearing essential oils (EOs) by using the light microscope (LM), and to identify EO constituents in their aerial parts using gas chromatography-mass spectrometry (GC-MS), for taxonomic delimitation among these species. The essential oils of the species with the highest EO yield were tested in-vitro against a human hepatocellular carcinoma (HepG 2) cell line.

resultsThe macro- and micromorphological characters of the stem and lamina were recorded. From these characters trichomes, ground system, and vascular bundles were diagnostic at the species level. GC-MS analysis detected the existence of 160 constituents prevailed by monoterpenes and sesquiterpenes classes in all species under investigation except in Citharexylum spinosum L. A, monoterpenes (2.19%) and sesquiterpenes (0.3%). In-vitro bioassay of EO against HepG 2 revealed a significant effect, as evidenced by the IC

conclusionsThis work revealed that Lamiaceae and Verbenaceae families are closely related, showing fluctuation in the mutual morpho-anatomical characteristics of the studied species, however, EO analysis showed variation among these species.

Indexed as

LamiaceaeOils, VolatilePhytochemicalsVerbenaceaeGas Chromatography-Mass SpectrometryHep G2 CellsHumansPlant LeavesOils, VolatilePhytochemicalsCytotoxicityEssential oilGC-MSHepG 2LamiaceaeMorphologyVerbenaceae

Identifiers

PMID42163085
PMCPMC13188656

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