Evidence map›Paper›PMID 42162509›Full record

ArticleSpine deformity2026

Sagittal malalignment in patients with adult spinal deformity seems to increase frontal instability during gait.

Georges El Haddad, Abir Massaad, Rami Rachkidi, Marc Boutros, Maria Asmar, Maria Karam, Emmanuelle Wakim, Jean Pierre Saad, Yamen Beyh, Joe Azar and 9 more

Abstract read
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Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

19 authors.

Georges El HaddadFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Abir MassaadFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Rami RachkidiFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Marc BoutrosFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Maria AsmarFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Maria KaramFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Emmanuelle WakimFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Jean Pierre SaadFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Yamen BeyhFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Joe AzarFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Mustapha RteilFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Gilles PrinceFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Ibrahim HamatiFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Guy AwadFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Nadim FreihaFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Marc MradFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Julien AbinahedItqan Clinical Simulation and Innovation Center, Hamad Medical Corporation, Doha, Qatar.
Ismat GhanemFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Ayman AssiFaculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon. ayman.assi@usj.edu.lb.ORCID http://orcid.org/0000-0002-3582-9420

Funding

Saint Joseph University FM361
6 · The paper itself

Abstract

purposeTo evaluate instability during gait and their determinants in ASD patients.

methods123 ASD patients and 42 controls underwent biplanar radiographs with calculation of spinopelvic and global alignment parameters, and performed 3D gait analysis to calculate full-body kinematics. They all filled the SF-36 with its physical component (PCS). The frontal and sagittal Center of Mass-Center of Pressure (CoM-CoP) angles were calculated during the gait cycle. Patients were classified as ASD-unstable or ASD-stable based on the corridor of normality of the CoM-CoP angle. Kinematics, radiographic parameters and PCS were compared between groups.

resultsAll ASD patients had a normal CoM-CoP angle in the sagittal plane. 38 ASD were classified as unstable in the frontal plane and 85 as stable (14 ± 3° vs 8 ± 2° resp., p < 0.001). While the 2 groups had a similar pelvic incidence (PI = 53°), ASD-unstable patients had an increased SVA (69 vs 20 mm), and global tilt (GT: 33 vs 24°, all p < 0.05), compared to ASD-stable. The frontal Cobb was similar between the 2 groups (Cobb = 17°). ASD-unstable also had an increased sagittal kinematic ODHA (10 vs 6°), and a decreased normalized step length (0.30 vs 0.34, both p < 0.05). They also had a decreased PCS (33 vs 37).

conclusionASD patients with increased global sagittal malalignment (SVA & GT) appear to have increased frontal instability during gait. Frontal instability during gait was associated with kinematic limitations in the sagittal plane and deterioration in quality of life. Future work will focus on changes in gait stability in ASD patients after corrective spinal malalignment surgery.

Indexed as

Bone MalalignmentGaitSpineAdultBiomechanical PhenomenaFemaleGait AnalysisHumansMaleMiddle AgedRadiography3D movement analysisAdult spinal deformityGaitSpineStability

Identifiers

PMID42162509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.