Evidence map›Paper›PMID 42162419›Full record

ArticleNature2026

Dopamine drives persistent remodelling of the maternal brain.

Jennifer C O'Chan, Giuseppina Di Salvo, Ashley M Cunningham, Sohini Dutta, Elizabeth Brindley, Benjamin H Weekley, Winnie Chen, Rasika R Iyer, Ethan Wan, Cindy Zhang and 3 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer C O'ChanNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. jennifer.chan2@mssm.edu.ORCID http://orcid.org/0000-0002-4365-5889
Giuseppina Di SalvoNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0009-0001-6948-4619
Ashley M CunninghamNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sohini DuttaNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Elizabeth BrindleyNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Benjamin H WeekleyNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-4550-5988
Winnie ChenNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rasika R IyerNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0009-0002-5174-5443
Ethan WanDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID http://orcid.org/0000-0003-3043-6115
Cindy ZhangNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Naguib MechawarDouglas Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-4960-756X
Gustavo TureckiDouglas Institute, Department of Psychiatry, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-4075-2736
Ian MazeNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ian.maze@mssm.edu.ORCID http://orcid.org/0000-0003-1490-7781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy and postpartum experiences represent transformative physiological states that impose lasting demands on the maternal body and brain, resulting in lifelong neural adaptations

Indexed as

BrainDopamineHippocampusNeuronal PlasticityAnimalsFemaleHistonesHumansMicePostpartum PeriodPregnancyProtein Processing, Post-TranslationalTranscription, GeneticDopamineHistones

Identifiers

PMID42162419
PMCPMC13253353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.