Evidence map›Paper›PMID 42162387›Full record

Trial reportJournal of patient-reported outcomes2026

The latent difference score model is a viable alternative to arithmetic difference score-based anchor-driven minimal important change calculation.

Levent Dumenci, Daniel L Riddle

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Journal of patient-reported outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Levent DumenciTemple University, Philadelphia, USA. ldumenci@temple.edu.
Daniel L RiddleVirginia Commonwealth University, Richmond, USA.

Funding

Center for Clinical and Translational ResearchUL1TR000058 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2015
$12.5M
Knee Arthroplasity Pain Coping Training (KAST Pain): A Randomized TrialUM1AR062800 · NIAMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI RIDDLE, DANIEL L · 2012 to 2016
$5.2M
NCATS NIH HHS UL1 TR000058NIAMS NIH HHS UM1 AR062800NIH HHS UM1AR062800 and UL1TR000058
6 · The paper itself

Abstract

backgroundTraditional MIC estimates contain measurement error from PROMs. The LDSM offers a viable alternative to estimate MIC controlling for measurement error. We also propose a conceptual framework for considering the multiple steps necessary to calculate anchor-based MICs. METHODOLOGY: Data from KASTPain, a no-effect multi-center randomized clinical trial of 364 participants with knee osteoarthritis and who underwent knee arthroplasty, were used to illustrate the LDSM to estimate MIC. Based on a structural equation modeling framework, we used LDSMs to estimate MICs of three commonly used patient-reported outcomes of pain and functional status.

resultsWe reported nine MIC estimates, three PROMs crossed with three post-intervention measurement occasions, from the LDSM. Results from the receiver operating curve analysis indicated that the area under curve was high (median: 0.88 range: 0.77-0.90) for all analyses.

conclusionsLatent variable modeling of PROM change excludes PROM measurement error and may offer advantages over more traditional forms of MIC estimation.

Indexed as

Arthroplasty, Replacement, KneeMinimal Clinically Important DifferenceOsteoarthritis, KneePatient Reported Outcome MeasuresFemaleHumansPain MeasurementMICOutcomePainPrognosis

Identifiers

PMID42162387
PMCPMC13369083

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.