ArticleCommunications biology2026
Mitochondrial Ca
Abstract read
In one paragraph
Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Mitochondrial Permeability Transition Pore in Platelets: Mechanisms, Physiological Roles, and Therapeutic Perspectives.Antioxidants (Basel, Switzerland) · 2025Review
- Mitochondrial calcium uniporter is required for thermogenic adaptation mediated by reactive oxygen species signaling.Journal of lipid research · 2025Article
Corrections and comments
- Update ofMitochondrial Ca2023
Authors and funding
15 authors.
Iuliia Polina *Lillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Jyotsna Mishra *Department of Physiology, University of Arizona, Tucson, AZ, USA.
Michael W CypressLillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Maria LandherrLillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Nedyalka ValkovDepartment of Medicine, Brown University Health and Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID 0000-0003-3947-9947
Isabel ChaputLillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0003-1890-3518
Bridget NietoLillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Brian RheeLillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Ameneh AhrariHeart Institute, Hypertension and Kidney Research Center, Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Nathan DeMichaelisLillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.ORCID 0009-0002-1914-2423
Kye-Im JeonHeart Institute, Hypertension and Kidney Research Center, Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Ulrike MendeDepartment of Medicine, Brown University Health and Warren Alpert Medical School of Brown University, Providence, RI, USA.
Peng ZhangDepartment of Medicine, Brown University Health and Warren Alpert Medical School of Brown University, Providence, RI, USA.
Bong Sook JhunHeart Institute, Hypertension and Kidney Research Center, Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.ORCID 0000-0001-9916-9962
Jin O-UchiHeart Institute, Hypertension and Kidney Research Center, Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, USA. jouchi@usf.edu.ORCID 0000-0001-7566-5400
Funding
Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI KOGUT, STEPHEN J · 2016 to 2025
$45.0MUncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI HARRINGTON, ELIZABETH O · 2013 to 2022
$21.3MResearch CoreP30GM114750 · NIGMS · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI SHAW, SUNIL K · 2015 to 2019
$4.5MRegulation of mitochondrial calcium uniporter in the heartR01HL136757 · NHLBI · UNIVERSITY OF MINNESOTA · PI O-UCHI, JIN · 2017 to 2021
$1.9MRole of ER-mitochondria contact sites in Right Ventricular FibrosisR01HL171710 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI Bong Sook Jhun, Jin O-Uchi · 2024 to 2026
$1.7MMitochondrial Fission, Calcium, ROS in Right Ventricular FibrosisR01HL160699 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI Bong Sook Jhun · 2023 to 2026
$1.5MRole of Mitochondrial c-Src in Right Ventricular Dysfunction in Pulmonary HypertensionR01HL169456 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI Gaurav Choudhary, Peng Zhang · 2024 to 2026
$1.3MAmerican Heart Association (American Heart Association, Inc.) 18CDA34110091American Physiological Society (APS) Shih-Chun Wang Young Investigator AwardAmerican Physiological Society (APS) Summer Undergraduate Research FellowshipNHLBI NIH HHS R01 HL136757NHLBI NIH HHS R01 HL160699NHLBI NIH HHS R01 HL169456NHLBI NIH HHS R01 HL171710NIGMS NIH HHS P20 GM103652NIGMS NIH HHS P30 GM114750NIGMS NIH HHS U54 GM115677U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL136757U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL160699U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL171710U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) 5P20GM103652U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) P30GM1114750
Abstract
MCU, originally known as CCDC109A, is widely recognized as the gene responsible for encoding a pore-forming subunit of a Ca
Indexed as
CalciumCalcium ChannelsCell MembraneMitochondriaAnimalsBlood PlateletsHEK293 CellsHumansPlatelet ActivationCalciumCalcium Channelsmitochondrial calcium uniporter
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.