Evidence map›Paper›PMID 42162081›Full record

ArticleScientific reports2026

Swallowing dynamics of burdock treated with a chelating agent in patients with dysphagia.

Kazuya Maekawa, Takanori Tsujimura, Anna Sasa, Yuto Ochiai, Haruka Sakai, Taku Suzuki, Jin Magara, Ryuichi Inoue, Kana Umetani, Makoto Inoue

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kazuya MaekawaDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan.
Takanori TsujimuraDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan. tsujimura@dent.niigata-u.ac.jp.
Anna SasaDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan.
Yuto OchiaiDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan.
Haruka SakaiDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan.
Taku SuzukiDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan.
Jin MagaraDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan.
Ryuichi InoueToyo Institute of Food Technology, 23-2,4-Chome, Minami-Hanayashiki, Kawanishi, Hyogo, 666-0026, Japan.
Kana UmetaniToyo Institute of Food Technology, 23-2,4-Chome, Minami-Hanayashiki, Kawanishi, Hyogo, 666-0026, Japan.
Makoto InoueDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medicine, Dentistry and Health Sciences, 2-5274 Gakkocho-dori, Chuo-Ku, Niigata, 951-8514, Japan.

Funding

Japan Society for the Promotion of Science 25K13339
6 · The paper itself

Abstract

Food modification is a common approach for patients with dysphagia. Treating vegetables with a chelating agent adjusts the hardness of food without altering its visual appearance. The current study aimed to evaluate the swallowing dynamics of burdock treated with a chelating agent (Chelate) compared with texture-modified soft burdock (SoB) and hard burdock (HaB) products in patients with dysphagia. Additionally, we investigated saliva secretion and physical properties of foods after chewing in healthy participants. We examined a total of 141 patients and 10 healthy participants. Swallowing function of patients was evaluated using videoendoscopy. In patients, Chelate left less pharyngeal residue compared with SoB and HaB, whereas the initiation and movement of swallowing, swallowing safety, and oral residue did not differ among the three foods. In healthy participants, the stimulated saliva volume during chewing for Chelate was higher than that for SoB, and was equivalent to that for HaB. The bolus properties of Chelate after chewing exhibited higher water content than other foods. Chelate had lower cohesiveness than SoB and tended to be softer than HaB. We speculate that Chelate shows better efficacy of swallowing in patients with dysphagia because of saliva secretion and physical properties of the food bolus after chewing.

Indexed as

Chelating AgentsDeglutitionDeglutition DisordersAdultAgedFemaleHumansMaleMasticationMiddle AgedSalivaChelating AgentsChelating agentDysphagiaPharyngeal residueTexture-modified foodWater content

Identifiers

PMID42162081
PMCPMC13389018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.