ArticleScientific reports2026
Association between depression and subjective quality of life among older adults in Japan and Thailand: a cross-cultural multi-group structural equation modeling analysis.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The present study examined the association between depressive symptoms and subjective quality of life (QOL) among older adults in Japan and Thailand. It further analyzed the differences in this structural relationship across cultural contexts. We evaluated the impact of depression on a latent QOL construct and assessed the measurement and structural invariance between the two countries using structural equation modeling (SEM). A cross-sectional survey was conducted among older adults (aged ≥ 60) in urban and rural regions of Japan (n = 88) and Thailand (n = 57). Subjective QOL was assessed using the World Health Organization Quality of Life - Brief Version (WHOQOL-BREF) and modeled as a latent variable comprising five domains. Depressive symptoms were measured using the 15-item Geriatric Depression Scale (GDS-15). SEM with bootstrapping (1,000 resamples) was applied using R and a multi-group analysis was performed to evaluate cross-national differences. Depressive symptoms showed a significant negative effect on latent QOL in the total sample (β = -0.248, p = .008). However, cross-national comparison using chi-square difference test revealed a significant difference in the effect size between Japan (β = -0.49) and Thailand (β = -0.11; Δχ²1= 6.87, p = .008). Thus, measurement invariance was partially supported. Cultural background influences the relationship between depression and QOL. These findings highlight the need for culturally sensitive mental health strategies for older adults.
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