Evidence map›Paper›PMID 42161237›Full record

ArticleJournal of Ayurveda and integrative medicine

Integrated and Ayurveda standalone interventions compared with standalone modern care in Rheumatoid arthritis: Observations from a non-random, parallel group, open label, historical control study.

Sanjeev Rastogi, Krishna Gopal Sharma, Gurmeet Ram

Abstract read
In one paragraph

Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sanjeev RastogiAyurveda -Arthritis Treatment and Advanced Research Center, State Ayurvedic College and Hospital, Lucknow, 226003, India. Electronic address: rastogisanjeev@rediffmail.com.
Krishna Gopal SharmaAyurveda -Arthritis Treatment and Advanced Research Center, State Ayurvedic College and Hospital, Lucknow, 226003, India.
Gurmeet RamAyurveda -Arthritis Treatment and Advanced Research Center, State Ayurvedic College and Hospital, Lucknow, 226003, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatoid arthritis patients frequently visit Ayurveda clinics. Many such patients arrive at Ayurveda clinics after getting a trial of conventional modern medicine and being unsatisfied with the responses. In real world setting, many of these patients prefer to continue modern medicine along with Ayurveda interventions. This patient pool forms a very specific population of RA.

objectiveThe study was aiming at observing the benefits of adding Ayurveda interventions to ongoing modern medicine or Ayurveda alone intervention in those who preferred to stop modern medicine. MATERIAL AND

methodIt was a non-random, single center, parallel group, open label, historical control observational study where the past modern intervention was taken up as the historical control for all those who continued with Ayurveda alone or integrated intervention. The outcome assessment was done on the basis of Swollen Joint count, Tender joint count, VAS score, Patient Global Assessment, ESR and DAS-28. Both intergroup and intragroup comparison of all parameters was done.

results31 patients who were included in the study (17 in Ayurveda alone group and 14 in integrated management group) were compared for all outcomes within the group and also for inter group. These observations were also compared with historical control. Except historical control, both active intervention groups were found to have statistically significant improvements in pre-post analysis. An intergroup comparison was not able to find any significant difference except for DAS-28 which was found significantly different in three groups.

conclusionAyurveda interventions in RA are found to be more effective comparing to modern interventions alone observed through historical control. Integrative management of RA comprising of Ayurveda and modern standard care is only marginally better than Ayurveda alone and is much better than modern alone intervention in RA.

Identifiers

PMID42161237
PMCPMC13213756

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.