Evidence map›Paper›PMID 42161029›Full record

ArticleJACC. Advances2026

Intracardiac Versus Transesophageal Echocardiography for Left Atrial Appendage Occlusion: A Meta-Analysis.

Hatem Yaser, Shehab Yaser, Hazem E Mohammed, George Hanen, Mohamed E Haseeb, Mohamed Nasser, Elsayed S Moubarak, Mira M Abu Mahfouz, Mazen Negmeldin Yassin, AlMothana Manasrah and 2 more

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Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hatem YaserFaculty of Medicine, Assiut University, Assiut, Egypt.
Shehab YaserFaculty of Medicine, Assiut University, Assiut, Egypt.
Hazem E MohammedFaculty of Medicine, Assiut University, Assiut, Egypt.
George HanenFaculty of Medicine, Minia University, Minia, Egypt; Medical Research Group of Egypt (MRGE), Negida Academy, Arlington, Massachusetts, USA.
Mohamed E HaseebFaculty of Medicine, Minia University, Minia, Egypt.
Mohamed NasserFaculty of Medicine, Minia University, Minia, Egypt.
Elsayed S MoubarakFaculty of Medicine, Cairo University, Cairo, Egypt; Medical Research Group of Egypt (MRGE), Negida Academy, Arlington, Massachusetts, USA.
Mira M Abu MahfouzFaculty of Medicine, Yarmouk University, Irbid, Jordan.
Mazen Negmeldin YassinFaculty of Medicine, Cairo University, Cairo, Egypt.
AlMothana ManasrahUnited Health Services-Wilson Medical Center, Johnson City, New York, USA.
Islam Y ElgendyDivision of Cardiovascular Medicine, Gill Heart and Vascular Institute, University of Kentucky, Lexington, Kentucky, USA. Electronic address: iyelgendy@gmail.com.
Ahmed Sami AbuzaidAlaska Heart and Vascular Institute, Anchorage, Alaska, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal imaging modality for guiding left atrial appendage occlusion remains unclear.

objectivesThe authors compared the effectiveness and safety of intracardiac echocardiography (ICE) vs transesophageal echocardiography (TEE) during left atrial appendage occlusion.

methodsElectronic databases were searched through November 2025 for studies that compared procedural success and safety with ICE vs TEE. We pooled data using a random-effects model to calculate ORs for categorical outcomes and mean differences (MDs) for continuous variables. A subgroup analysis was performed for unadjusted and adjusted data.

resultsThe meta-analysis included 27 observational studies, of which 9 studies reported adjusted summary estimates. Procedural success was comparable in both groups (unadjusted OR: 1.16; 95% CI: 0.92-1.45, I

conclusionsICE and TEE demonstrated comparable procedural success. However, ICE was associated with shorter procedural duration at the expense of a higher incidence of intervention-requiring pericardial effusion and residual iatrogenic atrial septal defect. (Intracardiac versus Transesophageal Echocardiography for Left Atrial Appendage Occlusion: A Meta-Analysis Stratified by Adjusted and Unadjusted Subgroups; CRD420251243170).

Indexed as

atrial fibrillationintracardiac echocardiographyleft atrial appendage occlusionpericardial effusionprocedural timetransesophageal echocardiography

Identifiers

PMID42161029
PMCPMC13217600

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