Evidence map›Paper›PMID 42160438›Full record

ArticleScience advances2026

Systemic-to-local nanorobot thrombolysis.

Di Zhang, Ouling Zhu, Fangzhi Mou, Xinyi Wang, Chuan Cao, Wei Yi, Manyi Yang, Yun Liu, Xinkang Du, Xiao Wang and 5 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Di ZhangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.ORCID 0009-0001-2041-9349
Ouling ZhuDepartment of Orthopedics, General Hospital of Chinese PLA Central Theater Command, Wuhan 430070, P. R. China.ORCID 0009-0008-2486-1039
Fangzhi MouState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.ORCID 0000-0002-9644-8277
Xinyi WangSchool of Life Science and Biotechnology, Dalian University, Dalian 116622, China.ORCID 0000-0002-7389-6018
Chuan CaoState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.
Wei YiDepartment of Orthopedics, General Hospital of Chinese PLA Central Theater Command, Wuhan 430070, P. R. China.
Manyi YangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.ORCID 0000-0001-7342-7839
Yun LiuState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.ORCID 0000-0002-8536-9143
Xinkang DuState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.
Xiao WangDepartment of Orthopedics, General Hospital of Chinese PLA Central Theater Command, Wuhan 430070, P. R. China.ORCID 0009-0002-1727-1766
Jianfeng LiuState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.
Ding WangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.
Wei LuoState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.
Zhi LiDepartment of Orthopedics, General Hospital of Chinese PLA Central Theater Command, Wuhan 430070, P. R. China.ORCID 0000-0002-9327-8110
Jianguo GuanState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, P. R. China.ORCID 0000-0002-2223-4524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic micro/nanorobots hold promise for targeted thrombolysis, yet face challenges of rapid immune clearance and poor degradability, often necessitating invasive localized deployment and retrieval. Here, we present safe and versatile systemic-to-local thrombolysis enabled by magnetic nanorobots constructed from polyvinyl pyrrolidone-shielded porous Fe

Indexed as

Thrombolytic TherapyTissue Plasminogen ActivatorAnimalsAutonomous RobotsHumansNanoparticlesPovidonePovidoneTissue Plasminogen Activator

Identifiers

PMID42160438
PMCPMC13189132

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.