In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
25 authors.
Leticia Pérez-SisquésCentre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, London SE1 9RT, UK.ORCID 0000-0002-9682-9811 Shail U BhattCentre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, London SE1 9RT, UK.ORCID 0000-0002-4399-133X Angela CarusoResearch Coordination and Support Service, Istituto Superiore di Sanità, 00161 Rome, Italy.
Josephine L RobbClinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK.ORCID 0000-0002-6955-7355 Alex P A DonovanMRC Laboratory of Molecular Biology (LMB), Cambridge Biomedical Campus, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, UK.
Rosemary BamfordClinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK.
Alejo Torres-CanoCentre for Gene Therapy and Regenerative Medicine, King's College London, London SE1 9RT, UK.ORCID 0000-0003-4857-3177 Shoshana SpringMouse Imaging Centre (MICe), Hospital for Sick Children, Toronto, Ontario M5T 3H7, Canada.ORCID 0000-0002-8803-5552 Eleanor HendyClinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK.
Talia E GileadiCentre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, London SE1 9RT, UK.ORCID 0000-0002-8155-6822 Martyna PanasiukMRC Centre for Neurodevelopmental Disorders, New Hunt's House, King's College London, London SE1 1UL, UK.ORCID 0000-0003-0148-5356 Jed TrengoveClinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK.ORCID 0009-0000-5174-3005 Neeru JindalClinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK.ORCID 0009-0008-0097-5162 Mohi U AhmedCentre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, London SE1 9RT, UK.ORCID 0000-0003-2028-6475 Mara SabbioniResearch Coordination and Support Service, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0009-0007-0980-942X Joyce Taylor-PapadimitriouComprehensive Cancer Centre, King's College London, Great Maze Pond, London SE1 1UL, UK.
Diana CashBiomarker Research And Imaging in Neuroscience (BRAIN) Centre, Department of Neuroimaging, King's College London, London, SE5 9NU, UK.ORCID 0000-0001-5021-1234 Nicholas CliftonClinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK.ORCID 0000-0003-2597-5253 Jacob EllegoodMouse Imaging Centre (MICe), Hospital for Sick Children, Toronto, Ontario M5T 3H7, Canada.ORCID 0000-0003-1504-3321 Laura C AndreaeMRC Centre for Neurodevelopmental Disorders, New Hunt's House, King's College London, London SE1 1UL, UK.ORCID 0000-0003-3686-3927 Jason P LerchMouse Imaging Centre (MICe), Hospital for Sick Children, Toronto, Ontario M5T 3H7, Canada.
Maria Luisa ScattoniResearch Coordination and Support Service, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-6659-0280 K Peter GieseDepartment of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, King's College London, 5 Cutcombe Rd, London SE5 9RT, UK.
Cathy FernandesSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London SE5 8AB, UK.ORCID 0000-0001-7318-3352 M Albert BassonCentre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, London SE1 9RT, UK.ORCID 0000-0001-9834-7528 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Loss-of-function mutations in genes encoding lysine demethylases specific for trimethylated lysine 4 of histone 3 (H3K4me3) are associated with neurodevelopmental conditions, including autism spectrum disorder (ASD) and intellectual disability (ID). To study the role of KDM5B (lysine demethylase 5B)-mediated H3K4me3 demethylation, we investigated neurodevelopmental phenotypes in mice without KDM5B demethylase activity. These mice exhibited autism-like behaviors and increased brain size. H3K4me3 levels and the expression of neurodevelopmental genes were increased in the developing
Indexed as
Autism Spectrum DisorderAutistic DisorderJumonji Domain-Containing Histone DemethylasesNuclear ProteinsReceptors, N-Methyl-D-AspartateRepressor ProteinsAnimalsDisease Models, AnimalDNA-Binding ProteinsHistonesMaleMemantineMiceNeocortexPhenotypeSynaptosomesDNA-Binding Proteinshistone H3 trimethyl Lys4HistonesJumonji Domain-Containing Histone DemethylasesKdm5b protein, mouseMemantineNuclear ProteinsReceptors, N-Methyl-D-AspartateRepressor Proteins
Identifiers
PMID42160407
PMCPMC13189110
What OpenQuestion holds
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