Evidence map›Paper›PMID 42160361›Full record

ArticleJournal of Parkinson's disease2026

Handgrip strength and relationship with non-motor symptoms in Parkinson's disease.

Daniele Urso, Roberta Barone, Davide Vilella, Valentina Gnoni, Alessia Giugno, Lucia Batzu, Salvatore Minnella, Karolina Popławska-Domaszewicz, Kallol Ray Chaudhuri, Giancarlo Logroscino

Abstract read
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In one paragraph

Article in Journal of Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniele UrsoCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.ORCID 0000-0002-4503-0110
Roberta BaroneCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.ORCID 0009-0003-6265-5221
Davide VilellaCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.
Valentina GnoniCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.ORCID 0000-0003-3181-0842
Alessia GiugnoCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.ORCID 0000-0002-9366-1582
Lucia BatzuDepartment of Neurosciences, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, UK.ORCID 0000-0001-6249-2803
Salvatore MinnellaPrinciples and Practice of Clinical Research (PPCR), TH Chan Harvard School of Public Health, Boston, MA, USA.
Karolina Popławska-DomaszewiczDepartment of Neurology, Poznan University of Medical Sciences, Poznan, Poland.ORCID 0000-0002-9154-389X
Kallol Ray ChaudhuriDepartment of Neurosciences, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Giancarlo LogroscinoCenter for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundMuscle weakness, particularly reduced handgrip strength (HGS), is a prominent clinical feature in Parkinson's disease (PD). While the relationship between motor symptoms and muscle strength has been extensively studied, the connection between HGS and non-motor symptoms (NMS) remains less explored.ObjectiveThis study investigates the relationship between HGS and NMS in PD patients, hypothesizing that higher burden of NMS is associated with a reduced HGS.MethodsFifty consecutive PD patients were enrolled and underwent comprehensive neurological and neuropsychological evaluations, 3T MRI scans, routine laboratory tests, and

Indexed as

Cognitive DysfunctionDepressionHand StrengthParkinson DiseaseAgedFemaleHumansMaleMiddle AgedNeuropsychological TestsQuality of LifeTomography, Emission-Computed, Single-PhotoncognitiondepressionParkinson's diseasesarcopenia

Identifiers

PMID42160361
PMCPMC13435165

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.