ArticlePloS one2026
Dynamic right ventricular and atrial volume responses to exercise in endurance-trained and untrained healthy individuals.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
aimsLeft ventricular (LV) function is enhanced during exercise in endurance-trained (ET) compared to untrained (UT) healthy individuals. However, the volume responses of the right ventricle (RV), left atrium (LA), and right atrium (RA) during exercise have not been studied in the same subject simultaneously and while standardizing for the respiratory influence on cardiac volumes. The aim was therefore to investigate how the four-chambered heart responds to exercise in ET and UT healthy individuals using exercise real-time cardiac magnetic resonance imaging (CMR) while controlling for effects of respiration. MATERIALS AND
methodsTwenty ET (9 women) and 13 UT healthy individuals matched for age and sex underwent CMR at rest and during moderate and vigorous exercise. LV and RV end-diastolic and end-systolic volumes (EDV and ESV), stroke volumes (SV) and maximal and minimal LA and RA volumes (LAVmax, RAVmax and LAVmin, RAVmin) were measured at end expiration.
resultsLVEDV and LVESV decreased during exercise in both groups. RVEDV and RVESV decreased during exercise in ET but was unchanged in UT. LAVmax and LAVmin were unchanged from rest to vigorous exercise in both groups. RAVmax decreased during exercise in ET whilst RAVmin was unchanged, and RAVmax and RAVmin were unchanged in UT. Thus, the RV and RA volume responses during exercise differed between ET and UT.
conclusionThis study shows differences between ET and UT healthy individuals in adaptations to exercise when examining the four chambers simultaneously and even when standardizing for respiratory influences. This contributes to increased understanding of the RV volume adaptations in ET.
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