Evidence map›Paper›PMID 42160242›Full record

Trial reportReproduction & fertility2026

ESPriT1: the effectiveness of laparoscopic treatment of isolated superficial peritoneal endometriosis for managing chronic pelvic pain in women: a randomised controlled feasibility trial.

Lucy H R Whitaker, Linda J Williams, Jacqueline Stephen, Jane P Daniels, Andrew W Horne

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Reproduction & fertility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucy H R WhitakerCentre for Reproductive Health, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-7678-6551
Linda J WilliamsEdinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-6317-1718
Jacqueline StephenEdinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0003-4997-3017
Jane P DanielsNottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0003-3324-6771
Andrew W HorneCentre for Reproductive Health, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-9656-493X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lay summary: Endometriosis is a chronic pain condition that affects >190 million people worldwide. It is recommended in clinical guidelines to remove the most common type of endometriosis, 'superficial peritoneal endometriosis' (SPE), if it is diagnosed at laparoscopy (keyhole surgery). However, the evidence to support removal of SPE is based on small studies with short-term follow-up. The aim of this small feasibility trial was to determine what proportion of women with pelvic pain undergoing laparoscopy for suspected endometriosis would be willing to be randomly allocated to have surgical removal of SPE or not have it treated surgically straightaway (sham surgery). Of the eligible patients that were approached, 31% consented to take part, demonstrating that people with endometriosis are willing to take part in a sham surgical trial. We are now leading a similar, but much larger UK-wide trial, to determine whether removal of SPE truly improves painful endometriosis symptoms.

Indexed as

Chronic PainEndometriosisLaparoscopyPelvic PainPeritoneal DiseasesAdultFeasibility StudiesFemaleHumansTreatment Outcomechronic pelvic painendometriosisfeasibility RCTlaparoscopysuperficial peritoneal endometriosis

Identifiers

PMID42160242
PMCPMC13232596

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.