ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Targeting Supramolecular Active Complexes of Na
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Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
28 authors.
Liting SunThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Hang XianDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Yunxin ShiThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Taotan YangThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Hongyan ShuaiPre-clinical College, Dali University, Dali, Yunnan, China.
Wenchao HuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Siying FeiThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Miao XuThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Taoyuan YangThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Ruilong XiaThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Ting WenThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Fengting ZhuThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Yan FuThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Yang LiThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Wei XiaThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Ran QianThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Yuanying LiuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Zhicheng TianDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Lamei LiDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Qian ZhouThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Lize XiongDepartment of Anesthesiology and Perioperative medicine, Shanghai Fourth People's Hospital, Shanghai, China.
Rui CongDepartment of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Ceng LuoDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Shengxi WuDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Xiafeng ShenThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.
Xin YuPre-clinical College, Dali University, Dali, Yunnan, China.
Rou-Gang XieDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Changgeng PengThe First Rehabilitation Hospital of Shanghai, Brain and Spinal Cord Innovation Research Center, Translational Research Institute of Brain and Brain-Like Intelligence，Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center For Anesthesiology and Perioperative Medicine, School of Medicine, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0002-6707-2717
Funding
Excellent Youth Science Foundation of Shaanxi Province 2025JC-JCQN-103Major National Science and Technology Projects of China 2018ZX09733001-006-005National Natural Science Foundation of China 31871063National Natural Science Foundation of China 32070977National Natural Science Foundation of China 51971236National Natural Science Foundation of China 82060149National Natural Science Foundation of China 82101320National Natural Science Foundation of China 8213012National Natural Science Foundation of China 82171212National Natural Science Foundation of China 82221001National Natural Science Foundation of China 82293640National Natural Science Foundation of China 82293643National Natural Science Foundation of China 82302681National Natural Science Foundation of China 82371225National Natural Science Foundation of China 82571386Shanghai Fourth People's Hospital Sykyqd11201Shanghai Fourth People's Hospital SY-XKZT-2025-1003Shanghai Municipal Commission for Science and Technology 19411951800the Scientific and Technological Innovation 2030-major project of Brain Science and Brain-Like Intelligence Technology 2021ZD0202804The second round of the three-year action plan for "strengthening and promoting Traditional Chinese Medicine" of Hongkou District HKGYQYXM-2022-06
Abstract
Neuropathic pain (NP) affects 7%-10% of population, with current treatments often proving inadequate. Here we show that Na
Indexed as
Chronic PainGanglia, SpinalNAV1.7 Voltage-Gated Sodium ChannelNAV1.8 Voltage-Gated Sodium ChannelNeuralgiaAnimalsDisease Models, AnimalHumansMaleMiceNeuronsNAV1.7 Voltage-Gated Sodium ChannelNAV1.8 Voltage-Gated Sodium Channelchronic painCrebDsppathological hallmarkSptan1targeted therapyTrkB
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.