Evidence map›Paper›PMID 42159723›Full record

ReviewHistochemistry and cell biology2026

Visualisation of peroxisomes: a journey through seven decades.

Xinyu Tang, Markus Islinger, Michael Schrader

Abstract readReview
In one paragraph

Review in Histochemistry and cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinyu TangFaculty of Health and Life Sciences, Department of Biosciences, University of Exeter, Exeter, EX4 4QD, UK.
Markus IslingerInstitute of Neuroanatomy, Mannheim Center for Translational Neuroscience, Medical Faculty Mannheim, University of Heidelberg, 68167, Mannheim, Germany.
Michael SchraderFaculty of Health and Life Sciences, Department of Biosciences, University of Exeter, Exeter, EX4 4QD, UK. M.Schrader@exeter.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council (BBSRC) BB/W015420/1, BB/T002255/1, APP75647China Scholarship Council Project ID: 202306760051
6 · The paper itself

Abstract

Peroxisomes are ubiquitous, oxidative organelles in eukaryotes with conserved functions in cellular lipid metabolism and redox balance. They are now recognised as key metabolic organelles of medical importance, with contributions to antiviral signalling, pathogen defence, innate immunity, cancer and neurodegeneration. Our current knowledge of peroxisomes and the molecular understanding of their diverse functions and roles in disease have been achieved through a combination of biochemical and morphological studies. This review provides a comprehensive overview of the morphological techniques and approaches developed over the past 70 years to specifically label, identify and visualise peroxisomes in mammals, yeast and plants. We discuss the historical milestones that led to the first visualisation of peroxisomes in these organisms and trace the evolution of imaging strategies from early cytochemical and electron microscopy methods to modern fluorescence-based and high-resolution techniques. By highlighting the contribution of these approaches to advances in peroxisome biology, this review aims to place current peroxisome visualisation methods in a historical and methodological context.

Indexed as

PeroxisomesAnimalsHumansPlantsYeastsCytochemistryElectron microscopyImmunolabellingMammalianPeroxisomesPlantYeast

Identifiers

PMID42159723
PMCPMC13190783

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.