ArticleSleep & breathing = Schlaf & Atmung2026
The triadic relationship between obesity, obstructive sleep apnea and metabolic dysfunction-associated steatotic liver disease in children: a scoping review.
Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A dynamic triad: why weight trajectory matters in pediatric obesity, sleep apnea, and metabolic risk.Sleep & breathing = Schlaf & Atmung · 2026Article
- Outcome of Targeted Therapy for Obstructive Sleep Apnea in Children with Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).Children (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this scoping review is to provide a comprehensive overview of existing research exploring the potentially triadic relation between obesity, OSA, and MASLD in children.
methodsA systematic literature search of PubMed and Web of Science was conducted in accordance with the PRISMA Extension for Scoping Review (PRISMA-ScR) guidelines. Following title and abstract screening, eligible studies were subjected to full-text assessment, resulting in the inclusion of 15 studies in the final review.
resultsThe initial search identified 263 studies, of which 15 met the inclusion criteria following title and abstract screening and full-text review. Data extraction enabled a comprehensive synthesis of current evidence on the pairwise associations and the potential triadic relationship between obesity, OSA, and MASLD in children. The findings suggest that oxidative stress and inflammation are key underlying mechanisms contributing to this triadic interplay.
conclusionKey causative factors identified for the triad between pediatric obesity, OSA, and MASLD encompass adipocyte dysfunction, hypoxia-induced IR, and inflammation. However, certain ambiguities remain. Future research should clarify the underlying mechanisms, including fat distribution and the gut-liver axis, and investigate the impact of intermittent hypoxia on adipose tissue to inform treatment strategies targeting all components of the triad.
Indexed as
Identifiers
42159625What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.