Evidence map›Paper›PMID 42159619›Full record

ArticleAntonie van Leeuwenhoek2026

Function and transcription of stoS gene of Xanthomonas campestris pathovar campestris.

Kai-Xuan Lin, Hsiao-Ching Chang, Chih-En Li, Chao-Tsai Liao, Yi-Min Hsiao

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Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kai-Xuan LinDepartment of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung, 406, Taiwan.
Hsiao-Ching ChangDepartment of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung, 406, Taiwan.
Chih-En LiDepartment of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung, 406, Taiwan.
Chao-Tsai LiaoDepartment of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung, 406, Taiwan.
Yi-Min HsiaoDepartment of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung, 406, Taiwan. ymhsiao@ctust.edu.tw.

Funding

National Science and Technology Council NSTC112-2313-B-166-001
6 · The paper itself

Abstract

StoS is a hybrid histidine kinase that, to date, has been investigated only in Xanthomonas oryzae pathovar oryzae. In this study, we elucidated the function and transcriptional regulation of the stoS gene in X. campestris pathovar campestris (Xcc). An stoS deletion mutant and its complemented strain were constructed to assess phenotypic characteristics. Inactivation of StoS markedly decreased tolerance to heat, sodium dodecyl sulfate, and hydrogen peroxide, impaired membrane integrity, and reduced stationary-phase survival, whereas complementation restored these phenotypes. Transcriptional mapping identified a guanine residue 22 nucleotides upstream of the start codon as the transcription start site. Promoter activity assays further revealed that stoS expression is regulated by nutrient availability and environmental stress. Together, these results demonstrate that stoS plays a crucial role in maintaining membrane stability and stress resilience in Xcc. By providing the first functional characterization of stoS in Xcc, this study extends its investigation beyond X. oryzae pathovar oryzae and advances current understanding of stress-adaptive regulation in Xanthomonas.

Indexed as

Bacterial ProteinsHistidine KinaseTranscription, GeneticXanthomonas campestrisGene DeletionGene Expression Regulation, BacterialHydrogen PeroxidePromoter Regions, GeneticStress, PhysiologicalBacterial ProteinsHistidine KinaseHydrogen PeroxidePromoterReporter assayStress toleranceXanthomonas

Identifiers

PMID42159619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.