Evidence map›Paper›PMID 42159495›Full record

ArticleApplied and environmental microbiology2026

Hydrazinoacetic acid is a biosynthetic precursor of the bacterially produced nitramine,

Gabriel Padilla, Benjamin M Rathman, Shivaiah Vaddypally, Brenda Martinez Rodriguez, Michael J Zdilla, David E Graham, Jonathan D Caranto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriel Padilla *Department of Chemistry, University of Central Florida, Orlando, Florida, USA.
Benjamin M Rathman *Department of Chemistry, University of Central Florida, Orlando, Florida, USA.
Shivaiah VaddypallyDepartment of Chemistry, Temple University, Philadelphia, Pennsylvania, USA.
Brenda Martinez RodriguezDepartment of Chemistry, University of Central Florida, Orlando, Florida, USA.
Michael J ZdillaDepartment of Chemistry, Temple University, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-0212-2557
David E GrahamBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0001-8968-7344
Jonathan D CarantoDepartment of Chemistry, University of Central Florida, Orlando, Florida, USA.ORCID 0000-0002-9196-5275

Funding

Mechanisms of novel biological nitrogen chemistriesR35GM147515 · NIGMS · UNIVERSITY OF CENTRAL FLORIDA · PI Jonathan D Caranto · 2022 to 2026
$1.8M
National Science Foundation CHE-2215854NIGMS NIH HHS R35 GM147515NIH HHS R35GM147515Office of Naval Research N00014-22-1-2266Strategic Environmental Research and Development Program WP2332Strategic Environmental Research and Development Program WP24-4206
6 · The paper itself

Abstract

Nitramines [R(R')N-NO IMPORTANCE: Chemical manufacture of nitramine energetics produces hazardous waste streams. Mitigation of these waste streams could be accomplished by replacing current production processes with enzymatic or synthetic biology approaches, enabling sustainable production of these compounds. This study identifies a

Indexed as

Aniline CompoundsGlycineStreptomycesBiosynthetic PathwaysMultigene FamilyNitrobenzenesTandem Mass SpectrometryAniline CompoundsGlycinenitramineNitrobenzenesbiosynthesisbiotechnologyenergetic materialenergeticsnatural productnitraminesecondary metabolism

Identifiers

PMID42159495
PMCPMC13274452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.