Evidence map›Paper›PMID 42159377›Full record

ArticlemBio2026

The synergistic action of reduced membrane permeability and antibiotic sequestration as a novel mechanism for carbapenem resistance in

Xinggui Chen, Yulian Zhou, Quan Zhou, Min He, Mengyu Zhao, Suchuan Dai, Jinpeng Li, Chengyao Hou, Weilai Tao, Xinyi Yang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xinggui ChenKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.ORCID 0009-0007-6364-4232
Yulian ZhouKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Quan ZhouKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Min HeKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Mengyu ZhaoKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Suchuan DaiKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Jinpeng LiKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Chengyao HouKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Weilai TaoKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Xinyi YangKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Shiying LanKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Xin YangKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Changwei LeiKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Anyun ZhangKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.ORCID 0000-0002-8814-517X
Hongning WangKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.ORCID 0000-0002-7244-9929
Yizhi TangKey Laboratory of Bioresource and Eco-environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.ORCID 0000-0003-0805-7020

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbapenems are last-resort antibiotics against gram-negative pathogens, including multidrug-resistant IMPORTANCE:

Indexed as

Anti-Bacterial AgentsCampylobacterCarbapenemsCell Membrane PermeabilityBacterial Proteinsbeta-LactamasesMeropenemMicrobial Sensitivity TestsMolecular Dynamics SimulationMutationPorinsWhole Genome SequencingAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsMeropenemPorinsCampylobactercarbapenem resistanceouter membrane proteinsOXA-61synergism

Identifiers

PMID42159377
PMCPMC13251398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.