Siloxane-tethered poly(2-ethyl-2-oxazoline) as surface modifying additives for anti-fouling silicones.

Jenlyan Negrón Hernández, Anika S Palacharla, Darian K Kanu, Shane J Stafslien, Lyndsi Vander Wal, Melissa A Grunlan

Abstract read

In one paragraph

Article in European polymer journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jenlyan Negrón HernándezDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.

Anika S PalacharlaDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas 77843, United States.

Darian K KanuDepartment of Materials Science and Engineering, Texas A&M University, College Station, Texas 77843, United States.

Shane J StafslienDepartment of Coatings and Polymeric Materials, North Dakota State University, Fargo, ND 58108, United States.

Lyndsi Vander WalDepartment of Coatings and Polymeric Materials, North Dakota State University, Fargo, ND 58108, United States.

Melissa A GrunlanDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.

Funding

Improving Outcomes in Cataract Surgery: Intraocular Lenses (IOLs) Resistant to Cell GrowthR21EY034598 · NEI · TEXAS ENGINEERING EXPERIMENT STATION · PI GRUNLAN, MELISSA · 2023 to 2024

$494k

NEI NIH HHS R21 EY034598

6 · The paper itself

Abstract

While silicones are broadly utilized for medical devices, their hydrophobic nature renders them highly prone to biofouling, leading to reduced safety and efficacy. We have previously demonstrated that biofouling is reduced for silicones combined with amphiphilic surface modifying additives (SMAs) comprised of a poly(ethylene glycol) (PEG) segment and a siloxane tether (PEG-silane). However, there is a rising concern regarding the potential immunogenicity of PEG. Herein, SMAs were created wherein poly(2-ethyl-2-oxazoline) (PEtOx) was substituted for PEG. PEtOx-silane SMAs (H-Si-DMS

Indexed as

AmphiphilicAntifoulingPoly(2-ethyl-2-oxazoline)SiliconesSurface modifying additives

Identifiers

PMID42158959

DOI10.1016/j.eurpolymj.2026.114638

PMCPMC13183407

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.