Evidence map›Paper›PMID 42158860›Full record

ArticleFrontiers in immunology2026

Metabolomics discover distinct metabolite profiles in children with different airway allergic diseases.

Yida Zhang, Peiyan Zheng, Jian-Lin Wu, Yixuan Ren, Manyun Jiang, Shiyun Li, Baoqing Sun

Erratum issuedAbstract read
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Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yida Zhang *College of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, China.
Peiyan Zheng *Faculty of Chinese Medicine, School of Pharmacy & State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau SAR, China.
Jian-Lin WuFaculty of Chinese Medicine, School of Pharmacy & State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau SAR, China.
Yixuan RenThe First Clinical Medical College of Kunming Medical University, Kunming, China.
Manyun JiangDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National, Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Shiyun LiDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National, Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Baoqing SunDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National, Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR), asthma, and their combined allergic rhinitis and asthma syndrome (CARAS) frequently coexist. However, the underlying pathophysiological and metabolic mechanisms, as well as reliable diagnostic differentiation, remain challenging. Carboxyl-containing metabolites (CCMs) have been implicated in the pathogenesis of these conditions; therefore, this study aimed to comprehensively profile serum CCMs in pediatric patients. Sera from 63 children with AR, 41 with asthma, and 90 with CARAS, sensitized to

Indexed as

AsthmaMetabolomeMetabolomicsRhinitis, AllergicAdolescentAnimalsBiomarkersChildChild, PreschoolFemaleHumansMaleBiomarkersairway allergic diseasederivatizationmetabolic pathwaymetabolomicspediatric patients

Identifiers

PMID42158860
PMCPMC13180947

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.