Evidence map›Paper›PMID 42158828›Full record

ReviewInternational journal of medical sciences2026

The Rare RNA Methylations m²G, Cm, m⁵U and ms²i⁶A: Roles in Disease Pathogenesis and Emerging Therapeutic Implications.

Keyu Wan, Tiantian Nie, Qin Zhang, Ying Huang, Jing Bian, Jia Min

Abstract readReview
In one paragraph

Review in International journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Keyu WanDepartment of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Tiantian NieThe First Clinical Medical College, Nanchang University, Nanchang, China.
Qin ZhangDepartment of Oncology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Ying HuangThe First Clinical Medical College, Nanchang University, Nanchang, China.
Jing BianThe First Clinical Medical College, Nanchang University, Nanchang, China.
Jia MinDepartment of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA methylation modifications play a central and multifaceted role in various physiological processes by precisely regulating key steps in the RNA life cycle, including nuclear processing, nuclear export, splicing, and cytoplasmic translation. These modifications, which occur on the four nucleotides that constitute RNA strands, are tightly regulated by specific proteins known as "writers," "readers," and "erasers." Advances in high-throughput sequencing and mass spectrometry technologies have progressively unveiled the biological functions of common RNA methylation marks such as N6-methyladenosine (m

Indexed as

NeoplasmsRNA5-MethylcytosineAdenosineAnimalsCytidineEpitranscriptomeGuanosineHumansRNA MethylationRNA Processing, Post-TranscriptionalUridine2-methylthio-N6-isopentenyladenosine5-MethylcytosineAdenosineCytidineGuanosineRNAUridine2-methylthio-N6-isopentenyladenosine (ms2i6A)2′-O-methylcytidine (Cm)5-methyluridine (m5U)detection methodsdiseasesN2-methylguanosine (m2G)RNA modification

Identifiers

PMID42158828
PMCPMC13181387

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.