Evidence map›Paper›PMID 42158814›Full record

Trial reportInternational journal of medical sciences2026

The Effects of a Prebiotic Formula Promoting

Chih-Kuan Wu, I-Shiung Cheng, Yu-Chun Chung, Megan F Liu, Yung-Kai Lin, Yung-Hsiang Lin, Kristin Morris, Di Chang, Chi-Fu Chiang, Ming-Ta Yang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chih-Kuan WuDepartment of Urology, Taipei Medical University Hospital, Taipei, Taiwan.
I-Shiung ChengDepartment of Physical Education, National Taichung University of Education, Taichung City, Taiwan.
Yu-Chun ChungCenter for General Education, Taipei Medical University, Taipei, Taiwan.
Megan F LiuSchool of Gerontology and Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan.
Yung-Kai LinInstitute of Food Safety and Risk Management, National Taiwan Ocean University, Keelung, Taiwan.
Yung-Hsiang LinResearch & Design Center, TCI Co., Ltd., Taipei, Taiwan.
Kristin MorrisAmway Innovation and Science, Ada, MI, USA.
Di ChangResearch & Design Center, TCI Co., Ltd., Taipei, Taiwan.
Chi-Fu ChiangResearch & Design Center, TCI Co., Ltd., Taipei, Taiwan.
Ming-Ta YangCenter for General Education, Taipei Medical University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gut health is closely associated with metabolic homeostasis, and alterations in gut microbiota composition have been linked to inflammation and metabolic disorders. Prebiotics targeting specific taxa, such as Methods: Seventy participants were randomized to receive either placebo or the AKK formula for 8 weeks. Anthropometric assessments, blood tests, and stool examinations were performed at baseline and at weeks 4 and 8. The main analyses were conducted in the per-protocol population (n = 25 per group). Results: The results revealed no significant markers of liver or kidney dysfunction in either group. The AKK formula group showed an increased qPCR-derived relative abundance of Conclusions: The AKK formula increased the relative abundance of

Indexed as

Gastrointestinal MicrobiomePrebioticsAdultAkkermansiaBifidobacteriumFecesFemaleHumansMaleMiddle AgedVerrucomicrobiaPrebioticsAkkermansia muciniphilagut microbiotaprebiotic supplementationrandomized controlled trial

Identifiers

PMID42158814
PMCPMC13181376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.