ArticleGastroenterology report2026
Changes in bowel-movement frequency, gut microbiota, and emotional issues in postoperative constipation patients.
Article in Gastroenterology report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In recent years, the prevalence of chronic constipation among adults worldwide has shown a yearly increasing trend, with most patients experiencing varying degrees of emotional disorders. Understanding the underlying mechanisms linking chronic constipation, gut microbiota, and emotional status is crucial for developing effective therapeutic strategies. Objectives: To investigate the clinical efficacy of surgical intervention for slow-transit constipation and evaluate its postoperative impacts on bowel function, gut microbiota composition and function, and host immune status. Methods: This study aimed to explore the relationship between gut microbiota and emotional status by collecting preoperative and postoperative clinical data, psychological conditions, and gut microbiota profiles from 30 patients undergoing total colectomy with ileorectal anastomosis for chronic constipation. Clinical and microbiota data were analysed to evaluate changes in emotional status and gut microbiota composition before and after surgery. Results: The results demonstrated that the anxiety and depression levels of patients significantly improved following surgery. Concurrently, gut microbiota diversity noticeably decreased, accompanied by significant alterations in species composition. Postoperative changes revealed that Conclusions: This study suggests that constipation surgery not only improves bowel movements, but also alters the composition of gut microbiota and ameliorates mood disorders in patients. These findings provide novel insights into the interplay between gut microbiota and emotional well-being, highlighting the potential of targeting gut microbiota as a therapeutic approach for managing psychological conditions associated with chronic constipation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.