Evidence map›Paper›PMID 42158758›Full record

ArticleCureus2026

Beyond Painful Bones and Renal Stones: Acute Crystal Arthropathy of Dual Aetiology May Be an Unforeseen Complication Following Parathyroid Surgery.

Amy Sara Varghese, Rebecca John, Thomas Paul, Paul M Jacob, Elanthenral Sigamani, Kripa Cherian

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amy Sara VargheseEndocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Vellore, IND.
Rebecca JohnEndocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Vellore, IND.
Thomas PaulEndocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Vellore, IND.
Paul M JacobEndocrine Surgery, Christian Medical College, Vellore, Vellore, IND.
Elanthenral SigamaniPathology, Christian Medical College, Vellore, Vellore, IND.
Kripa CherianEndocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Vellore, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hyperparathyroidism (PHPT), one of the most common endocrine conditions, has myriad manifestations, including nephrolithiasis, osteoporosis, neuropsychiatric complications and fatigue. The treatment of choice is focused parathyroidectomy when the lesion is localised. Common complications following parathyroidectomy include hypoparathyroidism and hungry bone syndrome. Acute crystal arthropathy due to gout and pseudogout following parathyroid surgery is scarcely reported. We report the case of a 47-year-old man who developed painful swelling of bilateral ankle joints following parathyroidectomy for PHPT. Synovial fluid aspirate from the ankle joint showed positively birefringent rhomboid-shaped calcium pyrophosphate dihydrate (CPPD) crystal and needle-shaped crystal of mono-sodium urate on polarised light microscopy. He was initiated on analgesics and glucocorticoids and had symptomatic improvement. The development of acute painful swelling of the joints following parathyroidectomy should alert the clinician to the possibility of gout and pseudogout; the timely recognition and treatment will aid in quick recovery.

Indexed as

acute crystal arthropathycalcium pyrophosphate dihydrate diseasegoutgout crystalsgout flareprimary hyperparathyroidismpseudogout

Identifiers

PMID42158758
PMCPMC13182670

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.