ArticleTranslational pediatrics2026
Incremental value of body composition indices in discriminating poorly controlled asthma in children: a cross-sectional study.
Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Asthma is the most common chronic respiratory disease in children, yet a considerable proportion of children have poorly controlled asthma despite advances in treatment. Traditional assessment models based on clinical indicators and lung function parameters show limited discriminatory ability. This study evaluated whether bioelectrical impedance analysis (BIA)-derived body composition indices-extracellular water-to-total body water ratio (ECW/TBW), phase angle (PhA), and visceral fat area (VFA)-improve the discrimination of poorly controlled asthma in children beyond traditional clinical assessments. Methods: This cross-sectional study enrolled 103 children aged 6-14 years with asthma, categorized into poorly controlled (n=41) and well-controlled (n=62) groups. Two logistic regression models were constructed: a base model [age, sex, forced expiratory volume in 1 second (FEV Results: Children with poorly controlled asthma had elevated ECW/TBW (0.40 Conclusions: BIA-derived body composition indices provided incremental discriminatory value for poorly controlled asthma beyond traditional assessment, potentially reflecting underlying systemic inflammation and metabolic disturbances. These findings warrant confirmation through multicenter studies with external validation.
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