Evidence map›Paper›PMID 42158699›Full record

ArticleTranslational pediatrics2026

Risk factors for complications after laparoscopic surgery in children with congenital choledochal cysts.

Jie Li, Bingyu Zhang, Jinfeng Li, Pingqian Bao, Jinchao Zhao

Abstract read
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Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jie LiDepartment of Pediatric Surgery, Leshan Women and Children Hospital, Leshan, China.
Bingyu ZhangDepartment of Pediatric Surgery, Leshan Women and Children Hospital, Leshan, China.
Jinfeng LiDepartment of Pediatric Surgery, Leshan Women and Children Hospital, Leshan, China.
Pingqian BaoDepartment of Pediatric Surgery, Leshan Women and Children Hospital, Leshan, China.
Jinchao ZhaoDepartment of General Surgery, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0009-0003-9448-2652

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Laparoscopic Roux‑en‑Y hepaticojejunostomy is the standard treatment for pediatric congenital choledochal cysts (CCCs). However, postoperative complications remain a significant clinical challenge. This study aimed to identify independent risk factors and develop a predictive model for complications following laparoscopic CCC excision in children. Methods: We conducted a retrospective cohort study of 362 pediatric patients who underwent laparoscopic surgery for CCC between August 2019 and July 2024 at two tertiary centers. Preoperative variables were systematically collected. Univariable and multivariable logistic regression analyses identified predictors of complications, with significant variables (P<0.05) incorporated into a nomogram for risk stratification. Subgroup and Cox regression analyses were used to evaluate factors for specific complications and time-to-event outcomes. Results: Postoperative complications occurred in 34 patients (9.39%). The most common were biliary-intestinal anastomotic stricture (35.3%), choledocholithiasis (23.5%), and pancreatitis (20.6%). Independent predictors included: cyst wall thickness >5 mm [odds ratio (OR) =4.23, 95% confidence interval (CI): 1.26-6.75; P<0.001], chronic cholecystitis (OR =6.42, 95% CI: 3.39-9.24; P<0.001), Todani type I (OR =6.13, 95% CI: 2.74-10.38; P=0.002), elevated C-reactive protein (CRP) (OR =1.52, 95% CI: 1.12-2.16; P=0.04), and elevated direct bilirubin (DB; OR =2.05, 95% CI: 1.23-4.17; P=0.04). Subgroup analysis confirmed cyst wall thickness, chronic cholecystitis, Todani type I, and CRP consistently predicted all complications, while DB was specifically linked to choledocholithiasis (P=0.02). Cox regression further associated cyst wall thickness >5 mm with higher complication risk (P=0.04). Conclusions: Cyst wall thickness >5 mm, chronic cholecystitis, Todani Type I, elevated CRP, and elevated DB were selected as factors to assess the prognosis of children with choledochal cysts, providing important reference value for the prognostic evaluation and clinical management of children with choledochal cysts.

Indexed as

chronic cholecystitisC-reactive protein (CRP)Cyst wall thicknessdirect bilirubin (DB)Todani type I

Identifiers

PMID42158699
PMCPMC13181631

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