ArticleTranslational pediatrics2026
A case report of X-linked agammaglobulinemia complicated with necrotic pneumonia.
Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: X-linked agammaglobulinemia (XLA) complicated with necrotic pneumonia caused by Bruton tyrosine kinase ( Case Description: This case report describes an 8-year-old boy diagnosed with agammaglobulinemia complicated by NP. The child had a history of recurrent cough, fever, and chest pain. Despite symptomatic and supportive treatment, his condition relapsed and progressed to NP. A definitive diagnosis was confirmed through genetic testing. Currently, reports of Conclusions: This case highlights the clinical significance of early assessment of immunoglobulin levels and lymphocyte immunophenotyping in children with a history of recurrent infections. For those suspected of having an immunodeficiency disorder, prompt genetic testing is strongly recommended to facilitate an accurate diagnosis. Such an approach not only aids in timely clinical decision-making but also helps optimize the patient's quality of life and improve long-term prognosis.
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