ArticleBMJ neurology open2026
Blood pressure variation and futile recanalisation in patients with large-vessel occlusion after endovascular therapy.
Article in BMJ neurology open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and purpose: Although systolic blood pressure variation (ΔSBP) has been regarded as a predictor of poor outcome after endovascular therapy (EVT), its effect at the different time intervals on the prognosis of acute anterior large vessel occlusion remains unclear. The study aims to assess the impact of ΔSBP at different time intervals on futile recanalisation (FRT) of acute anterior circulation large-vessel occlusion stroke after EVT. Methods: A total of 554 consecutive patients who achieved successful recanalisation after EVT were enrolled from the Effect of Endovascular Treatment Alone versus Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients with Acute Ischemic Stroke (DEVT) and Effect of Intravenous Tirofiban versus Placebo Before Endovascular Thrombectomy on Functional Outcomes in Large Vessel Occlusion Stroke (RESCUE BT) trials. ΔSBP was defined as SBP Results: Among these patients, 278 patients underwent FRT and 276 achieved useful recanalisation at 90 days. ΔSBP Conclusion: SBP variation within the first 6 hours after EVT was associated with FRT. Large fluctuations (ΔSBP >40 mm Hg) of SBP in 0-6 hours following EVT were found to increase the probability of FRT.
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