Trial reportFrontiers in oncology2026
A randomized controlled trial of telemedicine and e-health interventions for the management of oral complications in oncology patients undergoing antineoplastic therapy.
Trial report in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial: Understanding oral health challenges in pediatric and adult cancer care.Frontiers in oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Severe oral complications during and after antineoplastic therapies, such as mucositis, fungal, viral, and bacterial infections, xerostomia, dysphagia, and jaw osteonecrosis, significantly impair oral health and quality of life in oncology patients. Dentist involvement throughout oncology care is essential to reduce complications and support patient well-being. Telemedicine and e-health tools offer effective approaches for oral-health monitoring during treatment. Objective: To evaluate the effectiveness of a comprehensive dental intervention for the assessment and management of oral health in patients with solid tumors during cancer therapy using e-health applications, compared with standard oncology-based oral care. Methods: This prospective randomized interventional study was conducted at an Oncology Hospital in Athens (March 2022-November 2023), including 105 patients with breast, lung, or colon cancer initiating chemotherapy or combined therapy. Three clinical and radiographic oral-health and quality-of-life assessments were performed. The control group received standard recommendations to visit a dentist, while the intervention group followed a structured, individualized oral health - management protocol via telemedicine and clinical monitoring. Results: Telemedicine significantly improved oral-health outcomes and oral-care behaviors compared with controls. At mid-treatment and treatment completion, the intervention group showed statistically significant lower rates of mucosal lesions, gingival bleeding, gingivitis, dental caries, periodontitis, and higher tooth-brushing frequency. These results indicate that Telemedicine and e-health enable effective monitoring, early-stage detection, and oral self-care guidance, improving oral health and well-being during and after treatment. Conclusion: Integration of structured teledentistry monitoring into oncology care was associated with improved oral health outcomes in patients undergoing antineoplastic therapy, compared with usual practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.