ArticleFrontiers in oncology2026
Clinical management of metastatic gastric tumors: a case report of right popliteal leiomyosarcoma metastasizing to the stomach and literature review.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Gastric metastases are rare, accounting for only 0.2%-0.7% of gastric malignancies. Gastric metastasis from primary popliteal fossa leiomyosarcoma (LMS) has not been previously reported. We report a 60-year-old female who presented with hematemesis and severe anemia, with a past medical history of right popliteal fossa LMS resection. Imaging and endoscopy revealed a bleeding nodular lesion in the gastric body. Pathology and immunohistochemistry (SMA+/Desmin+, CD117-/DOG-1-) confirmed metastatic LMS to the stomach, with suspected pancreatic and bone metastases. The patient underwent emergency embolization for active bleeding, followed by laparoscopic partial gastrectomy and systemic chemotherapy. At the 9-month follow-up, she remained in good general condition. This case highlights that in patients with a history of malignancy presenting with gastrointestinal bleeding, gastric metastasis should be considered, and multidisciplinary management combined with surgery and systemic therapy can achieve favorable outcomes.
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