ArticlePublic health action2026
Tuberculosis preventive therapy in Sierra Leone: early implementation gaps and lessons learned.
Article in Public health action, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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18 authors.
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Abstract
backgroundIn 2023, Sierra Leone started tuberculosis preventive therapy (TPT) implementation. The tuberculosis programme recommends four contacts per index case for tracing and screening.
methodsThis study was to assess the performance of early implementation of contact tracing, screening, and TPT uptake in five regional hospitals.
resultsOf 905 index cases recorded, 1,222 contacts were traced and screened by community health workers. Of these, 433 were enrolled into TPT, and 353 (82%) completed the TPT regimen. Eighty out of 353 (18%) on TPT were lost to follow-up.
conclusionDeficiencies in documenting contacts and logistical constraints to trace, screen, and follow up for enrolment and completion of TPT need to be addressed for TPT scale-up.
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