Evidence map›Paper›PMID 42158250›Full record

ArticleFrontiers in nutrition2026

Black cumin (

Negin Hosseini, Zahra Emam-Djomeh, Gholamreza Askari, Ali Hashemi Nejad, Haniye Takbirgou, Raimar Lobenberg, Neal M Davies, Michael J Serpe, Maryam Salami

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Negin HosseiniDepartment of Food Science, Engineering, and Technology, College of Agriculture and Natural Resources, Karaj Campus, University of Tehran, Karaj, Iran.
Zahra Emam-DjomehDepartment of Food Science, Engineering, and Technology, College of Agriculture and Natural Resources, Karaj Campus, University of Tehran, Karaj, Iran.
Gholamreza AskariDepartment of Food Science, Engineering, and Technology, College of Agriculture and Natural Resources, Karaj Campus, University of Tehran, Karaj, Iran.
Ali Hashemi NejadDepartment of Food Science, Engineering, and Technology, College of Agriculture and Natural Resources, Karaj Campus, University of Tehran, Karaj, Iran.
Haniye TakbirgouDepartment of Food Science, Engineering, and Technology, College of Agriculture and Natural Resources, Karaj Campus, University of Tehran, Karaj, Iran.
Raimar LobenbergFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.
Neal M DaviesFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.
Michael J SerpeDepartment of Chemistry, University of Alberta, Edmonton, AB, Canada.
Maryam SalamiDepartment of Food Science, Engineering, and Technology, College of Agriculture and Natural Resources, Karaj Campus, University of Tehran, Karaj, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oleosomes, also known as oil bodies (OBs), are naturally occurring colloidal particles present in edible plant seeds and nuts and possess unique functional properties. In this study, oleosomes derived from black cumin (BCO) were extracted and used as novel, natural carriers for the encapsulation of hydrophobic compounds, using curcumin as a model bioactive. An optimized extraction method achieved a satisfactory recovery yield of approximately 38%, and the physicochemical characteristics of black cumin oleosome (BCO) and its associated proteins were systematically characterized. Curcumin is an unstable bioactive compound of turmeric with high sensitivity to degradation and metabolism, which needs to be encapsulated and protected within a matrix. Curcumin was well encapsulated into BCO using a different pH-shift method, resulting in a high encapsulation efficiency of 91%, without precipitation of curcumin, which was consistent with the FT-IR results, indicating that 10 mg of curcumin was successfully encapsulated within the interior core of oleosomes. Curcumin-loaded oleosomes demonstrated improved functional performance, including enhanced antioxidant stability and emulsifying properties.

Indexed as

bioavailability enhancementblack cumin oleosomecurcumingastrointestinal digestionNigella sativapH-shift encapsulation method

Identifiers

PMID42158250
PMCPMC13181737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.