ArticleEuropean heart journal. Imaging methods and practice2025
Four-dimensional phase-contrast MRI with accelerated dual velocity encoding in patients with complex congenital heart disease: a feasibility study.
Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aims: To evaluate, in complex congenital heart disease (CHD), the feasibility of a single free-breathing dual-VENC 4D-flow MRI acquiring low- and high-VENC data consecutively within the same acquisition, and to quantify how metrics from low vs. high VENC co-vary across vascular territories. Methods and results: We conducted a single-centre, retrospective cohort study on a 3T system. Seventeen dual-VENC scans were acquired; 16 scans were analysable after quality review. We quantified the velocity-to-noise ratio (VNR), forward flow, peak velocity (Vmax), and the coefficient of variation (CV) of net flow across 30 cardiac frames in the ascending aorta (AAo), superior vena cava (SVC), inferior vena cava (IVC), pulmonary veins (PV), portal trunk (PT), and hepatic veins (HV). VNR was compared between VENC settings using a paired Wilcoxon signed-rank test. Agreement of forward flow and Vmax between low- and high-VENC was summarized with Spearman's rank correlation coefficient ( Conclusion: Dual-VENC 4D-flow MRI is feasible and clinically useful in complex CHD. Low-VENC improves VNR and reduces variability for slow venous flows, while high-VENC is required to faithfully capture arterial jets. Together in a single acquisition, they extend velocity dynamic range and streamline comprehensive haemodynamic assessment.
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