Evidence map›Paper›PMID 42158187›Full record

SynthesisFrontiers in public health2026

Association between bisphenols A and the risk of endometriosis: results from an updated meta-analysis.

Yue Chen, Junle Wu, Yuxin Wang, Fuke Wang, Qingxin Yang, Yan Zhu, Qin Zhou, Chenyu Sun, Panpan Li

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue Chen *Department of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Junle Wu *Department of Clinical Medicine, The Second Clinical Medical School of Anhui Medical University, Hefei, China.
Yuxin Wang *Department of Clinical Medicine, The First Clinical Medical School of Anhui Medical University, Hefei, China.
Fuke Wang *Department of Critical Care Medicine, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Qingxin YangDepartment of Clinical Medicine, The Second Clinical Medical School of Anhui Medical University, Hefei, China.
Yan ZhuDepartment of Obstetrics and Gynecology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.
Qin ZhouDepartment of Obstetrics and Gynecology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.
Chenyu SunDivision of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinic, Rochester, MN, United States.
Panpan LiDepartment of Gynecology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent studies have disputed the association between bisphenol A (BPA) and endometriosis. This updated meta-analysis was conducted to investigate the impact of BPA exposure on endometriosis. Methods: This study evaluated BPA exposure and endometriosis risk, analyzing studies from Web of Science, PubMed, Embase, Cochrane Library, and Chinese databases (CNKI, CBM, Wanfang, VIP) through August 2025. Methodological quality was assessed via the Newcastle-Ottawa Scale (NOS) and the Agency for Healthcare Research and Quality Tool (AHRQ). Heterogeneity was quantified using Results: Seven studies comprising 2,488 participants were included in quantitative synthesis. The meta-analyses demonstrated that BPA exposure was associated with a statistically significant increase in endometriosis risk (OR = 1.36, 95% CI = 1.13-1.63, Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251019552, identifier PROSPERO (CRD420251019552).

Indexed as

Benzhydryl CompoundsEndometriosisEnvironmental ExposurePhenolsBisphenol A CompoundsFemaleHumansRisk FactorsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsPhenolsBPAendocrine-disrupting chemicalsendometriosisenvironmental exposuremeta-analyses

Identifiers

PMID42158187
PMCPMC13180928

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.