Evidence map›Paper›PMID 42158166›Full record

ArticleAnesthesiology and pain medicine2026

Analgesic Effect of Ultrasound-Guided Caudal Block Versus Quadratus Lumborum Plane Block in Lumbar Spine Surgery in Adult Patients: A Double-Blinded Prospective Comparative Study.

Alyaa Abdel Sattar Mohamed Hassan, Atef Mohamed Mahmoud, Samar Ahmed Ramadan Mohamed, Mohammed Awad Alsaied, Ahmed Ali Lotfy

Abstract read
In one paragraph

Article in Anesthesiology and pain medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alyaa Abdel Sattar Mohamed HassanFaculty of Medicine, Fayoum University, Fayoum, Egypt.ORCID https://orcid.org/0009-0006-4599-5701
Atef Mohamed MahmoudFaculty of Medicine, Fayoum University, Fayoum, Egypt.ORCID https://orcid.org/0000-0003-2711-4772
Samar Ahmed Ramadan MohamedFaculty of Medicine, Fayoum University, Fayoum, Egypt.ORCID https://orcid.org/0009-0009-3045-033X
Mohammed Awad AlsaiedFaculty of Medicine, Fayoum University, Fayoum, Egypt.ORCID https://orcid.org/0000-0002-1633-6102
Ahmed Ali LotfyFaculty of Medicine, Fayoum University, Fayoum, Egypt.ORCID https://orcid.org/0009-0007-3492-4315

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative pain following lumbar spine surgery (LSS) can significantly impact recovery and patient satisfaction. Ultrasound-guided regional techniques such as quadratus lumborum plane block (QLPB) and caudal block (UGCB) have been proposed to enhance postoperative analgesia while reducing opioid consumption and opioid-related adverse effects (AEs). Objectives: To compare the analgesic efficacy and safety of ultrasound-guided QLPB versus ultrasound-guided caudal block in adult lumbar spine stabilization surgery. Methods: This randomized, double-blinded, prospective comparative study included 111 adult patients (18 - 60 years, ASA physical status I - II) scheduled for elective lumbar spine stabilization surgery. Patients were randomly allocated into three equal groups: Control (standard analgesia), ultrasound-guided caudal block (UGCB), or ultrasound-guided QLPB. Blocks were performed under ultrasound guidance after induction of general anesthesia using 0.25% bupivacaine. The primary outcome was the time to first postoperative rescue analgesia. Secondary outcomes included postoperative pain scores using the Numerical Pain Rating Scale (NPRS), total 24-hour postoperative opioid (meperidine) consumption, intraoperative opioid requirements, hemodynamic variables, and block- or opioid-related adverse events over the first 24 postoperative hours. Results: The time until the initial rescue analgesia was significantly delayed with QLPB in comparison to control and Caudal, with medians of 15, 1, and 5 h, respectively (P < 0.001). The total 24-hour (meperidine) intake was significantly diminished with QLPB as opposed to Caudal and control (P < 0.05). Numerical Pain Rating Scale scores were significantly diminished in QLPB and Caudal as opposed to control at 30 min, 1, 2, 4, 8, and 24 h (P < 0.001), with comparability detected at 12 h and 18 h. Intraoperative fentanyl administration was markedly diminished in the QLPB and Caudal groups, in contrast to the control group (P < 0.001). The occurrence of nausea and vomiting exhibited comparability across groups. Conclusions: Both ultrasound-guided caudal block and QLPB significantly improved postoperative analgesia compared with standard analgesic management following lumbar spine stabilization surgery. However, QLPB provided longer-lasting analgesia and was associated with lower postoperative opioid consumption than caudal block, highlighting its advantage for prolonged postoperative pain control.

Indexed as

AnalgesicsAnesthesiaCaudalNerve BlockOpioidPostoperative PainQuadratus LumborumSpinal FusionUltrasonography

Identifiers

PMID42158166
PMCPMC13181817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.