ReviewFrontiers in neurology
Advances in research concerning the association between allergic rhinitis and chronic sinusitis and cognitive impairment.
Review in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- New advances in the treatment of chronic rhinosinusitis with nasal polyps from pathophysiology to biologic targeted therapy.Frontiers in allergy · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the prevalence of chronic rhinosinusitis (CRS) and allergic rhinitis (AR) continues to rise worldwide, more and more patients are reporting a lower quality of life. In addition to causing common nasal symptoms such as congestion and rhinorrhea, these illnesses also show a close association with cognitive function in several ways. However, the available evidence remains dispersed. This paper reviews existing research on the effects of AR and CRS on cognitive function, organized into five sections: disease characteristics, cognitive impacts, mechanism pathways, therapeutic interventions, and future directions. Clinical research suggests that AR has a significant association with children's academic performance, neurodevelopment, and cognitive function, with a potential correlation with cognitive impairments. Additionally, adults' anxiety, depression, and cognitive impairments show a negative correlation with AR and CRS. Numerous factors, such as sleep disturbances, the intensity of facial symptoms, the nose-brain communication axis, brain activity and connectivity, and other issues, may be linked to the causes of cognitive impairment. Furthermore, there has been some advancement in the study of how AR and CRS treatments, such as sinus surgery, intranasal corticosteroids, and antihistamines, affect cognitive function. This data suggests that AR and CRS are closely related to cognitive impairment. However, there is still a lack of solid research evidence connecting AR and CRS to cognitive dysfunction, and further exploration is needed regarding their pathogenesis and pharmacological treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.