Evidence map›Paper›PMID 42157999›Full record

ArticleAlcohol research : current reviews2026

Alcohol Misuse in Older Women: A Scoping Review of Correlates, Consequences, Treatment, and Prevention.

Cathryn Glanton Holzhauer, Madeleine Stein, Rachel Rosen, Hannah Grigorian, Marissa Iverson, Elizabeth E Epstein

Abstract readScoping Review
In one paragraph

Article in Alcohol research : current reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cathryn Glanton HolzhauerDepartment of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut, New York.
Madeleine SteinDepartment of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, New York.
Rachel RosenDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Hannah GrigorianMental Illness Research, Education and Clinical Center, VA Bedford Healthcare System, Bedford, Massachusetts.
Marissa IversonUConn Health Sciences Library, Farmington, Connecticut.
Elizabeth E EpsteinDepartment of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, New York.

Funding

Research Training in Complementary and Integrative MedicineT32AT000051 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GLORIA Y YEH · 1999 to 2026
$10.2M
Pilot StudiesP50AA027055 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HOLZHAUER, CATHRYN GLANTON, STEFFENS, DAVID C. · 2019 to 2023
$7.8M
NCCIH NIH HHS T32 AT000051NCCIH NIH HHS T32AT000051NIAAA NIH HHS P50 AA027055NIAAA NIH HHS P50AA027055
6 · The paper itself

Abstract

backgroundAlcohol use and alcohol use disorder (AUD) among older women (defined as age 50 and over) have increased substantially in recent years. Compared to men and younger women, older women negotiate biopsychosocial transitions that put them at greater risk of alcohol-related health conditions as they age and are less reliably screened and treated for heavy alcohol use and AUD.

objectivesThis scoping review represents a critical evaluation of research methodology and findings since 2004 on biopsychosocial correlates and consequences of alcohol misuse (i.e., heavy alcohol use, defined as four or more drinks on any day or eight or more drinks per week; and/or AUD) among older women. These findings, with a focus on their implications for treatment and prevention strategies among this at-risk population, are discussed. The goal of the review is to summarize current research as well as treatment and prevention options available for older women and to identify gaps in the literature and potential for future research. ELIGIBILITY CRITERIA: 2,579 research articles were reviewed for inclusion in the paper. Inclusion criteria required that a study's findings were relevant to the review's objectives, with analyses and results that had clinically relevant findings for older women with heavy alcohol use and/or AUD. SOURCES OF EVIDENCE: Authors searched PubMed, Embase, and PsycInfo for articles published between January 1, 1994, and August 5, 2024. CHARTING

methodsTwo authors developed the template for data extraction, and four authors charted data. Weekly meetings were used to establish, monitor, and maintain calibration among authors.

results127 articles met inclusion/exclusion criteria and were included in the final extraction and results summary. Evidence-based information is presented on (1) clinical presentation of older women with alcohol misuse; (2) biological correlates of alcohol use in older age; (3) psychosocial correlates and consequences, such as mood disorders, social networks, and other substance use; (4) increased risk of health conditions, such as breast cancer and depression; and (5) current state of treatment and prevention needs and efforts.

conclusionsThe research reviewed here indicates a need for further age- and sex-specific research in the field of alcohol use and AUD. After age 50, men and women continue to differ in important ways in relation to the correlates, consequences, and treatment of alcohol misuse. The current literature includes significant methodological limitations and inconsistencies. Research with samples of older women who drink at heavy levels may be particularly helpful in addressing these limitations. Existing prevention and treatment interventions may be good options for older women, but more research is needed.

Indexed as

Alcohol DrinkingAlcoholismAgedFemaleHumansagingalcoholfemaleolderseniorsubstancetreatmentwomen

Identifiers

PMID42157999
PMCPMC13182901

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.