ArticleFood science & nutrition2026
The Impact of Serum 25-Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study.
Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Vitamin D is essential for bone health, but its effects on bone mineral density (BMD) may exhibit regional variations. This study aims to ascertain whether a consistent relationship exists between serum vitamin D and BMD at various bone sites. Participants were recruited from the UK Biobank, a large prospective cohort study. Serum 25-hydroxyvitamin D levels were measured at baseline (2006-2010), and BMD at the lumbar, pelvis, spine, femur, and arm were evaluated via DXA. A multivariate regression analysis was employed to examine the relationship between serum 25-hydroxyvitamin D and BMD at five sites simultaneously. This retrospective cohort study included 20,131 participants. The fully adjusted model revealed that a 1 nmol/L increase in serum 25-hydroxyvitamin D was associated with a 0.24, 0.38, 0.37, 0.28, and 0.20 mg/cm
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