Evidence map›Paper›PMID 42157950›Full record

ArticleInternational journal of biological sciences2026

Sanggenol L Induces Endoplasmic Reticulum Stress and Triggers Cell Apoptosis in Glioblastoma by Binding to BiP.

Jingyang Xu, Hongbo Chang, Yi Du, Zihan Tang, Ziyang Qin, Yongzhao Wang, Fujing Wei, Xiaosong Hu, Jianbing Hou, Man Xu and 1 more

Abstract read
In one paragraph

Article in International journal of biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingyang XuState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Hongbo ChangState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Yi DuState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Zihan TangState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Ziyang QinState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Yongzhao WangState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Fujing WeiState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Xiaosong HuState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Jianbing HouState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.
Man XuJinfeng Laboratory, Chongqing 401329, China.
Hongjuan CuiState Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing 400715, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisEndoplasmic Reticulum StressGlioblastomaHeat-Shock ProteinsCell Line, TumorCell SurvivalEndoplasmic Reticulum Chaperone BiPEndoribonucleasesHumansMorusProtein Serine-Threonine KinasesTemozolomideEndoplasmic Reticulum Chaperone BiPEndoribonucleasesHeat-Shock ProteinsProtein Serine-Threonine KinasesTemozolomideBiPChemosensitivityGlioblastomaSanggenol L

Identifiers

PMID42157950
PMCPMC13181853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.