Evidence map›Paper›PMID 42157822›Full record

ArticleACS medicinal chemistry letters2026

Stereochemical Terminology in Chiral Drugs: Still Between Confusion and Misinterpretation.

Juan García de la Concepción, Anthony J Burke, Pedro Cintas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan García de la ConcepciónDepartamento de Química Orgánica e Inorgánica, Facultad de Ciencias, and Instituto del Agua, Cambio Climático y Sostenibilidad (IACYS), Universidad de Extremadura, 06006 Badajoz, Spain.ORCID https://orcid.org/0000-0001-6484-9546
Anthony J BurkeCoimbra Chemistry Centre-Institute of Molecular Sciences (CQC-IMS), Departamento de Química, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID https://orcid.org/0000-0001-8248-1116
Pedro CintasDepartamento de Química Orgánica e Inorgánica, Facultad de Ciencias, and Instituto del Agua, Cambio Climático y Sostenibilidad (IACYS), Universidad de Extremadura, 06006 Badajoz, Spain.ORCID https://orcid.org/0000-0002-2608-3604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Viewpoint addresses the importance of correct designations of stereochemistry in chiral drugs. Sources of confusion typically arise from merging disparate concepts such as handedness, configuration, and chiroptical properties. This Viewpoint recommends the consistent use of configurational labeling, while avoiding ambiguous and context-dependent nomenclature.

Indexed as

academic trainingchiral drugchiroptical rotationconfigurational notationmolecular handedness

Identifiers

PMID42157822
PMCPMC13181469

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.