ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2026
In Vitro Effects of Combining Resin Infiltration and At-Home Bleaching on Hydrogen Peroxide Penetration, Color Change and Enamel Morphology.
Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveTo evaluate the effect of resin infiltration (RI) prior to at-home bleaching on hydrogen peroxide (HP) penetration into the pulp chamber, color change, and enamel morphology in human teeth with sound enamel or white spot lesions (WSLs), using different RI protocols. MATERIALS AND
methodsSixty human premolars were randomly allocated into six groups (n = 10), according to enamel substrate (sound/WSLs) and treatment: at-home bleaching with 16% carbamide peroxide only (CP); RI with one prior acid-etching application followed by at-home bleaching (RI1/CP); and RI with three prior acid-etching applications followed by at-home bleaching (RI3/CP). HP penetration was quantified by UV-Vis spectroscopy. Color change was evaluated using a digital spectrophotometer (ΔE₀₀; WI
resultsRI significantly reduced HP penetration into the pulp chamber compared with CP alone, with reductions of over 90%, regardless of enamel substrate or RI protocol. Without RI, artificially induced WSLs showed greater HP diffusion than sound enamel (p < 0.05). Color outcomes (WI
conclusionsRI prior to at-home bleaching with 16% CP reduced HP penetration into the pulp chamber without compromising bleaching efficacy. Comparable color outcomes were achieved in teeth with WSLs, irrespective of prior acid-etching applications. CLINICAL SIGNIFICANCE: When combined with at-home bleaching, RI may reduce HP diffusion into the pulp chamber and improve esthetic integration of artificially induced WSLs through optical masking. However, these findings are based on an in vitro model and should be interpreted with caution regarding clinical outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.