ReviewFEBS open bio2026
Small RNA pathways in mammalian oocytes.
Review in FEBS open bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
RNA silencing pathways use small RNAs to guide sequence-specific repression of endogenous genes, mobile elements, and viruses. It has been 25 years since RNA interference (RNAi) was found in mouse oocytes and became the first identified small RNA pathway in mammals. Today, three distinct small RNA pathways are known to operate in mammalian oocytes-in addition to RNAi, there is the microRNA (miRNA) pathway and the PIWI-associated RNA (piRNA) pathway. These pathways differ mechanistically and functionally and their co-existence in the female germline evolved into different arrangements. This review aims to provide a basic introduction to mammalian RNA silencing pathways with a focus on mouse oocytes and key aspects of the pathways, which influence their biological roles in oocytes and zygotes, across mammals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.