Evidence map›Paper›PMID 42157443›Full record

ArticleEnvironmental microbiology reports2026

High Resistance and Biofilm Tolerance to Antimicrobials of Marine Bacteria From Brazilian Deep-Sea Sediment.

Amanda Simão Dias, Sílvia Dias de Oliveira, Renata Medina-Silva

Abstract read
In one paragraph

Article in Environmental microbiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amanda Simão DiasImunology and Microbiology Laboratory, School of Health and Live Sciences, Pontifical Catholic University of Rio Grande do Sul, PUCRS, Porto Alegre, Brazil.ORCID https://orcid.org/0000-0003-2307-4718
Sílvia Dias de OliveiraImunology and Microbiology Laboratory, School of Health and Live Sciences, Pontifical Catholic University of Rio Grande do Sul, PUCRS, Porto Alegre, Brazil.ORCID https://orcid.org/0000-0002-7296-5085
Renata Medina-SilvaImunology and Microbiology Laboratory, School of Health and Live Sciences, Pontifical Catholic University of Rio Grande do Sul, PUCRS, Porto Alegre, Brazil.ORCID https://orcid.org/0000-0002-5466-4908

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico Research Productivity Scholarships for SDO and RMSCoordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Petrobras 0050.0096017.15.9
6 · The paper itself

Abstract

Antimicrobial resistance studies have focused on clinical bacteria, neglecting the role of resistant isolates in natural environments. However, oceans are daily contaminated with high loads of antimicrobials and resistant bacteria from agro-industrial and urban activities. Deep-sea sediment is a challenging environment that may select microbial strains with resistance to chemicals and ability to form biofilms, becoming a potential reservoir of resistance genes. We evaluated the susceptibility to antimicrobials of six Pseudomonas sp., five Bacillus sp., two Brevibacillus sp. and two Paenibacillus sp. from deep-sea sediments of the Pelotas Basin (Brazil) by the disk diffusion and microdilution tests. Pseudomonas and Bacillales were tested against 11 and 7 antimicrobials, respectively. Biofilms of susceptible isolates were exposed to antimicrobials to determine the minimum biofilm inhibitory concentration (MBIC) and the minimum biofilm eradication concentration (MBEC). All Pseudomonas were resistant to aztreonam at very high concentrations (up to 2048 μg/mL). MBIC values were significantly higher than respective MICs, and only one third of biofilms were eradicated. These results underscore the importance of the study, as one of the first reporting antimicrobial tolerance of biofilms of cultivable bacteria from deep-sea sediments, contributing to the knowledge of bacterial resistance in these environments, concerning One Health issues.

Indexed as

Anti-Bacterial AgentsBacteriaBiofilmsDrug Resistance, BacterialGeologic SedimentsSeawaterBacillusBrazilMicrobial Sensitivity TestsPseudomonasAnti-Bacterial Agentsantimicrobialsbiofilm tolerancedeep‐sea bacteriamicrobial resistanceOne Health

Identifiers

PMID42157443
PMCPMC13580871

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.