Evidence map›Paper›PMID 42157379›Full record

ArticleThe Laryngoscope2026

Race and Ethnicity Affect Symptom and Endoscopy Associations in CT-Confirmed Chronic Rhinosinusitis.

Corey Karp, Mitchell Figueroa, Jaynelle Gao, Joshua S Lin, Zara Mubin, Sophia Albanese, Kevin Hur

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In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Corey KarpKeck School of Medicine, University of Southern California, California, Los Angeles, USA.
Mitchell FigueroaKeck School of Medicine, University of Southern California, California, Los Angeles, USA.
Jaynelle GaoKeck School of Medicine, University of Southern California, California, Los Angeles, USA.ORCID https://orcid.org/0000-0002-1853-4460
Joshua S LinCaruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine, University of Southern California, California, Los Angeles, USA.
Zara MubinKeck School of Medicine, University of Southern California, California, Los Angeles, USA.
Sophia AlbaneseKeck School of Medicine, University of Southern California, California, Los Angeles, USA.
Kevin HurCaruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine, University of Southern California, California, Los Angeles, USA.ORCID https://orcid.org/0000-0001-7016-4375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate demographic differences in the association between chronic rhinosinusitis (CRS) symptoms and endoscopic findings with CT-confirmed CRS.

methodsConsecutive adult patients presenting to outpatient rhinology clinics with chronic cardinal sinonasal symptoms who underwent nasal endoscopy and a sinus CT scan were included. Demographics, cardinal symptoms, SNOT-22, and Lund-Kennedy (LK) endoscopic scores were extracted from electronic medical records. Logistic regression was used to assess associations between predictors and CT-confirmed CRS (CT-CRS) with prespecified stratified analyses by race and ethnicity.

resultsAmong 314 included patients (mean age 48 ± 17 years, 51% female), 228 met criteria for CT-CRS. Hyposmia and LK endoscopic scores were associated with CT-CRS. However, in subgroup analyses, the associations of hyposmia and LK endoscopic scores with CT-CRS were not significant among Asian and Hispanic patients. Among patients with a negative nasal endoscopy, 62.6% had CT-CRS. In this subgroup, patient-reported nasal discharge and the presence of ≥ 2 cardinal symptoms were associated with reduced odds of CT-CRS.

conclusionsAssociations between symptoms and nasal endoscopy findings with CT-CRS were not significant among Asian and Hispanic patients, suggesting limitations of symptom and endoscopy-based assessments in these subgroups. Among patients with a negative nasal endoscopy, symptoms demonstrated limited ability to identify CT-CRS. These findings suggest CT imaging could be considered earlier in selected clinical contexts. LEVEL OF EVIDENCE: 3:

Indexed as

EndoscopyEthnicityRacial GroupsRhinitisRhinosinusitisSinusitisTomography, X-Ray ComputedAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedRetrospective Studieschronic rhinosinusitisLund–KennedyLund–Mackaynasal endoscopysinonasal imaging

Identifiers

PMID42157379
PMCPMC13669962

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.