Evidence map›Paper›PMID 42157324›Full record

ArticleJournal of nanobiotechnology2026

Dynamic modulation of immune-neural axis via controlled magnesium-releasing nanocapsules accelerates cranial bone regeneration.

Yilin Mao, Qixuan He, Tianle Li, Jiusi Guo, Yefeng Wu, Kelvin W K Yeung, Yuxiong Su, Jie Shen, Xianglong Han, Jian Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yilin MaoDivision of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Qixuan HeDivision of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Tianle LiDivision of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Jiusi GuoDivision of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Yefeng WuDivision of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Kelvin W K YeungOrthopaedics and Traumatology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Yuxiong SuOral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Jie ShenPeking University Shenzhen Hospital, Shenzhen, China.
Xianglong HanState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Sichuan Province, China.
Jian WangState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Sichuan Province, China.
Wei QiaoDivision of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China. drqiao@hku.hk.ORCID http://orcid.org/0000-0002-0450-0366

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2023A1515011963Hong Kong Innovation Technology Fund ITS/256/22National Natural Science Foundation of China 82201124National Natural Science Foundation of China/Research Grants Council Joint Research Scheme N_HKU721/23Research Grants Council, the Government of the Hong Kong SAR C7003-22YShenzhen Science and Technology Innovation Committee Projects SGDX20220530111405038the Food and Health Bureau, the Government of the Hong Kong SAR 09201466
6 · The paper itself

Abstract

Critical-sized cranial defects present a significant challenge in the field of bone tissue regeneration. Despite the emergence of various approaches to promote new bone formation, the clinical outcomes remain suboptimal. In this study, we developed an inorganic-organic hybrid bioink suitable for 3D printing of photocurable scaffolds. This bioink incorporates our novel nanocapsules with a shell consisting of amorphous whitlockite and PEG coating, which endows the scaffolds with superior mechanical strength and pro-osteogenic capacity. These nanocapsules enable a dual-phase Mg

Indexed as

Bone RegenerationMagnesiumNanocapsulesSkullAnimalsHumansMacrophagesMaleOsteogenesisPrinting, Three-DimensionalRatsRats, Sprague-DawleyTHP-1 CellsTissue ScaffoldsMagnesiumNanocapsules3D printingBone regenerationImmunomodulationMacrophageMagnesiumSensory nerve

Identifiers

PMID42157324
PMCPMC13366662

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.