Evidence map›Paper›PMID 42157181›Full record

ArticleBMC medical informatics and decision making2026

Automated algorithm in catheter-associated urinary tract infection identification using digital health records: validity and barriers in implementation into clinical practice.

Benedikt Wiggli, Lisa Alfare, Leandra Pfister, Nadine Schneider, Maria M Wertli, Joshua Ayoson

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Article in BMC medical informatics and decision making, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Benedikt Wiggli *Division of Infectious diseases, Cantonal Hospital of Baden, Baden, Switzerland.
Lisa Alfare *Department of Internal Medicine, Cantonal Hospital of Baden, Baden,, Switzerland.
Leandra PfisterDepartment of Internal Medicine, Cantonal Hospital of Baden, Baden,, Switzerland.
Nadine SchneiderDepartment of Internal Medicine, Cantonal Hospital of Baden, Baden,, Switzerland.
Maria M Wertli *Department of Internal Medicine, Cantonal Hospital of Baden, Baden,, Switzerland.
Joshua Ayoson *Department of Internal Medicine, Cantonal Hospital of Baden, Baden,, Switzerland. Joshua.ayoson@ksb.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to evaluate the accuracy of an automated algorithm designed to identify catheter-associated urinary tract infections (CAUTIs) using electronic health records from a hospital. We assess the algorithm's effectiveness as a clinical decision support tool by analyzing its ability to accurately identify CAUTIs based on predefined clinical parameters. MATERIALS AND

methodsWe conducted a retrospective analysis of all patients hospitalized in the acute internal medicine wards of the Cantonal Hospital of Baden between November 2022 and October 2024. Automated algorithm identifies potential CAUTI cases based on standard centers for disease control (CDC) criteria. The automated algorithm identified patients meeting these criteria as potential cases and the number of CAUTIs is visualized in a dash board. All records were manually reviewed and inconsistencies validated by an infection specialist. Sensitivity, specificity, area under the receiver operating characteristic (ROC) curve (AUC), likelihood ratios (LR) and 95% confidence intervals were calculated to assess performance.

resultsBetween November 2022 and October 2024, a cohort of 1424 patients with indwelling catheters was assessed, resulting in the identification of 11 manually diagnosed CAUTIs. The automated algorithm identified 6 of these cases, yielding 6 true positives (TP), 1,385 true negatives (TN), 28 false positives (FP), and 5 false negatives (FN). The algorithm demonstrated a sensitivity of 55% (95% CI: 27.3% - 81.8%) and a specificity of 98% (95% CI: 97.3% - 98.7%), positive likelihood ratio (LR+) of 27.3 and a negative likelihood ratio (LR-) of 0.5. AUC of 0.76 (95% CI: 0.73-0.80) with P-value of 0.0001.

conclusionIn this validation study, the automated algorithm demonstrated high specificity (98%) but limited sensitivity (55%) for the detection of CAUTIs. While a positive algorithm result was strongly associated with true infection, nearly half of confirmed CAUTI cases were not identified. Therefore, the algorithm may support surveillance by prioritizing cases for review; however, due to its limited sensitivity, it cannot reliably exclude non-cases and should not replace manual case adjudication. The primary reasons for missed cases were gaps in electronic health record (EHR) documentation. In hospitals with comprehensive EHR use across all departments, improved sensitivity is expected.

Indexed as

AlgorithmsCatheter-Related InfectionsDecision Support Systems, ClinicalElectronic Health RecordsUrinary Tract InfectionsAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityAlgorithmCatheterizationCAUTIDiagnosticsDigital-healthEpidemiologyInfection-controlInformaticsSurveillanceValidation

Identifiers

PMID42157181
PMCPMC13359772

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.