Evidence map›Paper›PMID 42157085›Full record

ArticleBMC genomic data2026

Comparative transcriptome analysis provides insights into the dwarfing mechanism of pear trees.

Yi Xiao, Qionghou Li, Shuo Li, Kaijie Qi, Yuan Gao, Hongxiang Li, Hanghang Du, Ke Ma, Shaoling Zhang, Xin Qiao

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomic data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

10 authors.

Yi Xiao *State Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Qionghou Li *State Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Shuo LiState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Kaijie QiState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Yuan GaoState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Hongxiang LiState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Hanghang DuState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Ke MaState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Shaoling ZhangState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China.
Xin QiaoState Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Jiangsu Key Laboratory for Horticultural Crop Breeding, Sanya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Jiangsu, 210095, China. qiaoxin@njau.edu.cn.

Funding

the Earmarked Fund for Agriculture Research System of China CARS-28the Jiangsu Agriculture Science and Technology Innovation Fund CX(22)2025the Major Scientific and Technological Project of Xinjiang 2024A02006the Seed Industry Promotion Project of Jiangsu JBGS(2021)022Zhongshan Biological Breeding Laboratory ZSBBL-KY2024-03
6 · The paper itself

Abstract

backgroundDwarfism is crucial for intensive cultivation and labor-saving management in modern orchards. However, the molecular mechanisms underlying pear tree dwarfing remain largely unclear. Here, we performed comparative transcriptome analysis between dwarf pear germplasm and pear cultivar 'Cuiguan'.

resultsThe dwarf pear germplasm exhibited significantly shorter internode and branch length compared to 'Cuiguan'. Histological analysis revealed that cortical cells in the dwarf pear germplasm were disordered and irregular, and longer than those of 'Cuiguan'. Comparative transcriptome analysis of shoot apex from young shoots of the dwarf germplasm and 'Cuiguan' was conducted and a total of 13,169 differentially expressed genes (DEGs) were identified. Functional enrichment analysis revealed that functional terms related to plant hormone biosynthesis and signal transduction were overrepresented in DEGs. Genes involved in brassinosteroid (BR) and gibberellin (GA) biosynthesis were downregulated in the dwarf germplasm. DEGs involved in transcription regulation and cell wall formation were also identified, which play potential roles in tree dwarfing. In addition, expression level of genes within the chromosomal region containing PcDw locus, which has been reported as the dominant gene controlling dwarf trait, was investigated in both the dwarf pear germplasm and 'Cuiguan'. Based on comparative analysis, nine genes in this region are considered to be closely associated with dwarf traits.

conclusionsThe dwarf germplasm and 'Cuiguan' showed distinct tissue structure, with dwarfism mainly associated with defects in cell division and elongation. Comparative transcriptome analysis identified a set of DEGs involved in plant hormones biosynthesis, signaling and transport, as well as cell wall biosynthesis, modification and degradation. By integrating transcriptome data with information related to the PcDW locus, nine genes were identified as key candidates. Overall, the results of this study provide insights for understanding the mechanisms underlying pear dwarfism.

Indexed as

Gene Expression ProfilingPyrusTranscriptomeGene Expression Regulation, PlantGibberellinsPlant Growth RegulatorsSignal TransductionGibberellinsPlant Growth RegulatorsComparative transcriptome‘Cuiguan’Dwarf germplasmDwarfing mechanismPear

Identifiers

PMID42157085
PMCPMC13366728

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